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肺功能相关遗传因素的研究进展

李盼英 张小峰 尹建运 任晓卫 杨静 倪倩

实用临床医药杂志2025,Vol.29Issue(3):133-137,143,6.
实用临床医药杂志2025,Vol.29Issue(3):133-137,143,6.DOI:10.7619/jcmp.20244444

肺功能相关遗传因素的研究进展

Research progress on genetic factors related to lung function

李盼英 1张小峰 2尹建运 3任晓卫 4杨静 5倪倩2

作者信息

  • 1. 兰州大学第二临床医学院,甘肃兰州,730000
  • 2. 兰州大学第二医院小儿呼吸科,甘肃兰州,730030
  • 3. 湖北省武汉市武昌医院儿科,湖北武汉,430064
  • 4. 兰州大学公共卫生学院,甘肃兰州,730000
  • 5. 兰州大学第二医院小儿肾脏病科,甘肃兰州,730030
  • 折叠

摘要

Abstract

Lung function serves as a clinical indicator reflecting respiratory system function,ai-ding in the diagnosis and monitoring of pulmonary diseases.Both genetic and environmental factors ex-ert significant influences on lung function.A comprehensive understanding of the role of genetic factors in lung function is crucial for gaining deeper insights into the regulatory mechanisms of lung function.In recent years,with the application of advanced technologies such as genome-wide association stud-ies,whole-exome sequencing,whole-genome sequencing,and epigenome-wide association studies,numerous genetic loci related to lung function have been identified.This review aimed to summarize the current research progress in genetics related to lung function,providing a reference for subsequent in-depth exploration of the pathological and physiological mechanisms affecting lung function.

关键词

肺功能/遗传/环境/全基因组

Key words

lung function/genetics/environment/whole genome

分类

医药卫生

引用本文复制引用

李盼英,张小峰,尹建运,任晓卫,杨静,倪倩..肺功能相关遗传因素的研究进展[J].实用临床医药杂志,2025,29(3):133-137,143,6.

基金项目

甘肃省自然科学基金项目(22JR5RA986) (22JR5RA986)

实用临床医药杂志

1672-2353

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