临床误诊误治2025,Vol.38Issue(6):38-42,5.DOI:10.3969/j.issn.1002-3429.2025.06.008
CT引导下同步穿刺活检联合射频消融术治疗肺结节效果及安全性分析
Effect and Safety of CT-guided Synchronous Puncture Biopsy Combined with Radiofrequency Ablation in the Treatment of Pulmonary Nodules
摘要
Abstract
Objective To investigate the effect and complications of computed tomography(CT)-guided synchronous puncture biopsy combined with radiofrequency ablation(RFA)in the treatment of pulmonary nodules.Methods In total,80 patients with pulmonary nodules admitted to the hospital from January to October 2023 were divided into the observation group(n=40)and the control group(n=40)according to surgical methods.The control group underwent CT-guided puncture bi-opsy followed by RFA,while the observation group underwent CT-guided synchronous puncture biopsy and RFA.The clinical efficacy,postoperative complications,and pulmonary function were compared between the two groups.Results All 80 pa-tients were diagnosed as malignant pulmonary nodules through pathological examination.There was no significant difference in the total effective rate between the two groups(P>0.05).The total incidence of pneumothorax,bleeding,pleural effusion and pulmonary infection in the observation group was lower than that in the control group[5.00%(2/40)vs.20.00%(8/40)](P<0.05).At 3 months after surgery,peak expiratory flow rate and forced vital capacity were lower in both groups than those before operation,which,however,were higher in the observation group than in the control group(P<0.01).Conclusion CT-guided synchronous puncture biopsy combined with RFA is effective in the treatment of pulmonary nodules,with few complications and relatively less damage to pulmonary function.关键词
肺结节/CT引导/射频消融/穿刺活检/气胸/胸腔积液/最大呼气流速峰值/用力肺活量Key words
Pulmonary nodule/CT-guided/Radiofrequency ablation/Needle biopsy/Pneumothorax/Pleural effu-sion/Peak expiratory flow rate/Forced vital capacity分类
临床医学引用本文复制引用
张阳,马保科,范敏,黄亚涛,李俊鹏..CT引导下同步穿刺活检联合射频消融术治疗肺结节效果及安全性分析[J].临床误诊误治,2025,38(6):38-42,5.基金项目
邯郸市科学技术研究与发展计划项目(23422083293) (23422083293)