摘要
Abstract
Objective Bleeding from rupture of cerebral arteriovenous malformations(cAVM)has been the most common cause of intracranial hemorrhage in children.The therapeutic goals should be preventing re-bleeding and improving quality-of-life.The objective of this study was to examine the differences in surgical ap-proaches for pediatric cAVMs.Methods From June 2022 to June 2024,retrospective analysis was performed for the relevant clinical data from 29 cAVM children undergoing endovascular embolization plus microsurgery.The relevant clinical data of blood loss volume,microscopic procedure time,hospitalization stay and outcomes were compared between two procedures.And patient outcomes were assessed by modified Rankin scale(mRS)at the time of discharge.Results The clinical grades were Ⅰ-Ⅲ(n=25)and Ⅳ(n=4).And they were assigned to undergo interventional embolization plus microsurgery(n=10)and operation alone(n=19).Volume of blood loss was(107.0±27.1)vs.(174.7±99.4)ml and the difference was statistically significant(t=2.780,P=0.011);microscopic operative duration[72.0(63.0,120.0)vs.140.0(102.0,160.0)min],Z=2.202,P=0.029];hospitalization stay[11.0(10.0,14.0)vs.16.0(13.000,23.0),Z=2.501,P=0.013].The prognosis-related factors were admission mRS score(x2=20.913,P＜0.001)and Spetzler-Martin score(x2=8.784,P=0.032).Conclusions For pediatric cAVM,endovascular embolization plus microsurgery is associated with shor-ter hospitalization stay,microscopic operative duration and less blood loss than surgery alone.关键词
脑动静脉畸形/显微外科手术/血管内操作/栓塞/治疗结果/对比研究Key words
Cerebral Arteriovenous Malformations/Microsurgery/Endovascular Procedures/Embol-ism/Treatment Outcome/Comparative Study
