摘要
Abstract
In recent years,chimeric antigen receptor(CAR)cell therapy,as an emerging immunotherapy method,has achieved significant results in the field of hematological cancer treatment.However,applying CAR cell therapy to autoimmune diseases remains a relatively novel and challenging method.Autoimmune diseases are caused by an individual's immune system mistakenly attacking their own tissues,and their complex etiology and diverse symptoms make traditional treatment methods and biologics still unable to meet clinical needs.CAR cell therapy,using engineering T cells or other immune cells to recognize and kill specific antigens,is highly targeted and durable,which providing new hope for the treatment of autoimmune diseases.This article systematically reviews the latest research progress and challenges of using CAR cell therapy in the treatment of autoimmune diseases,such as safety,immune response issues,and difficulties in clinical application.关键词
嵌合抗原受体/细胞疗法/自身免疫性疾病/安全性/临床应用Key words
Chimeric antigen receptor/Cell therapy/Autoimmune diseases/Safety/Clinical application分类
医药卫生
