器官移植2025,Vol.16Issue(2):214-219,6.DOI:10.12464/j.issn.1674-7445.2025083
肝癌肝移植的全流程管理
Full-process management of liver transplantation for hepatocellular carcinoma
摘要
Abstract
Hepatocellular carcinoma(HCC)is one of the most common cancers in clinical practice.Hepatectomy and liver transplantation are currently important treatment modalities for HCC.However,for patients with end-stage liver disease,liver transplantation is the optimal choice,as it can completely resect the tumor while restoring normal liver function.Nevertheless,clinical liver transplantation for HCC faces challenges such as a shortage of donor livers and a high risk of postoperative tumor recurrence and metastasis.How to select HCC patients for liver transplantation and effectively improve the prognosis of HCC liver transplantation has become a hot topic in clinical practice,involving multiple aspects from preoperative precise evaluation to long-term postoperative follow-up.Therefore,this article reviews the full-process management of HCC liver transplantation,including preoperative management,surgical management,postoperative management and the application of multidisciplinary comprehensive treatment in HCC liver transplantation,in order to provide references for improving the prognosis of HCC liver transplant recipients.关键词
肝细胞癌/肝移植/米兰标准/降期治疗/桥接治疗/复发转移/免疫抑制药/多学科综合诊疗Key words
Hepatocellular carcinoma/Liver transplantation/Milan criteria/Downstaging therapy/Bridging therapy/Recurrence and metastasis/Immunosuppressive agent/Multi-disciplinary treatment分类
医药卫生引用本文复制引用
吴广东,卢倩..肝癌肝移植的全流程管理[J].器官移植,2025,16(2):214-219,6.基金项目
研究型病房卓越临床研究计划项目(BRWEP2024W032240100) (BRWEP2024W032240100)