器官移植2025，Vol.16Issue(2)：229-236,8.DOI:10.12464/j.issn.1674-7445.2025013
从肿瘤免疫到器官移植免疫
From tumor immunity to organ transplantation immunity
摘要
Abstract
The major histocompatibility complex plays a crucial role in the immune response process,which is closely related to the occurrence and development of tumors and organ transplantation.Cellular immunity occupies an important position in tumor immunity and organ transplantation immunity,while humoral immunity also plays a significant role in organ transplantation immunity.Organ transplantation requires the induction and maintenance of immune tolerance,while tumors develop immune escape phenomena during their progression.In-depth exploration and comparison of the mechanisms of tumor immune escape and organ transplantation immune tolerance are of great significance for formulating reasonable immune tolerance induction strategies,improving the quality of life and prolonging the survival time of organ transplant patients.关键词
主要组织相容性复合体/肿瘤免疫/器官移植免疫/免疫逃逸/免疫耐受/排斥反应/抗原提呈细胞/树突状细胞Key words
Major histocompatibility complex/Tumor immunity/Organ transplantation immunity/Immune escape/Immune tolerance/Rejection/Antigen-presenting cell/Dendritic cell分类
医药卫生引用本文复制引用
周古翔,李一萱,郑瑾..从肿瘤免疫到器官移植免疫[J].器官移植,2025,16(2):229-236,8.基金项目
陕西省重点研发计划项目(2024SF2-GJHX-21) （2024SF2-GJHX-21）
国家自然科学基金(82170768) （82170768）
