日用化学品科学2025，Vol.48Issue(3)：33-38,6.DOI:10.3969/j.issn.1006-7264.2025.03.007
一款潮热喷雾降温和凉感的临床研究
Clinical study on a cooling and refreshing effects of a hot flash spray
赵雪华 1刘建伟 1郭萌 2彭先武 2吴梦洁 3林文强3
作者信息
- 1. 安利(上海)科技发展有限公司,上海 201203
- 2. 安利(中国)研发中心有限公司,广东 广州 510730
- 3. 上海盛评检测技术有限公司,上海 200433
- 折叠
摘要
Abstract
An instrumental assessment and volunteer subjective evaluation method was developed to synchronously measure the actual skin temperature and evaluate the cool sensation,conducting a quantitative analysis of the perceived coolness.This method was used to evaluate the effect of a self-developed hot flash spray on reducing the skin temperature and inducing the cooling sensation of menopausal individuals.31 healthy menopausal volunteers were recruited as the research subjects.Using infrared thermal imaging and electroencephalogram(EEG)measurements,the skin temperature and EEG data of the subjects'cheeks were simultaneously collected at baseline(BL),immediately after simulated hot flashes(HF),1 min(T1),3 mins(T3),and 5 min(T5)after the application of the test sample.The results showed that,compared with HF,the skin temperature of cheek was significantly reduced by 8.75%,8.75%,and 6.41%at T1,T3,and T5(P<0.05),respectively.And alpha-1 value of EEG was increased significantly by 59.70%,58.44%,and 51.39%at T1,T3,and T5(P<0.05),respectively.The hot flash spray effectively reduces skin temperature while also provides subjects with a feeling of coolness,which can relieve hot flashes in menopausal women.关键词
潮热/更年期/降温/凉感/瞬时受体电位褪黑素抑制素8(TRPM8)/脑电波(EEG)Key words
hot flash/menopause/cooling/sensation of coolness/transient receptor potential melastatin 8(TRPM8)/electroencephalogram(EEG)分类
化学工程引用本文复制引用
赵雪华,刘建伟,郭萌,彭先武,吴梦洁,林文强..一款潮热喷雾降温和凉感的临床研究[J].日用化学品科学,2025,48(3):33-38,6.
