摘要
Abstract
Objective:To investigate the clinical efficacy of early cranioplasty after decompressive craniectomy(DC)for patients with skull defects.Methods:The data of 82 patients with skull defect admitted to Liaocheng People's Hospital from May 2021 to May 2024 were retrospectively analyzed,and they were divided into a control group and a study group according to the different time of skull repair after DC operation,with 41 cases in each group.The control group underwent cranioplasty in the middle and late period(3～6 months)after DC operation,while the study group underwent cranioplasty in the early period(1～3 months)after DC operation.Cerebral blood flow velocity,neurological function,cognitive function,prognosis and the occurrence of complications were compared between the two groups.Results:Three months after operation,the average blood flow velocity of middle cerebral artery on the affected side and healthy side in both groups was faster than before operation,and the study group was faster than the control group,the differences were statistically significant(P<0.05).Three months after surgery,the score of the National Institutes of Health Stroke Scale in both groups was lower than before surgery,and the study group was lower than the control group,and the score of Mini-Mental State Examination in both groups was higher than before surgery,and the study group was higher than the control group,with statistical significance(P<0.05).At 3 months after operation,the scores of Karnofsky Performance Status and Glasgow Coma Scale in 2 groups were higher than those before operation,and the study group was higher than the control group,with statistical significance(P<0.05).The complication rate of the study group was 9.76%lower than 26.83%of the control group,and the difference was statistically significant(P<0.05).Conclusion:Early cranioplasty after DC surgery can more effectively improve cerebral blood flow velocity in patients with skull defect,promote the recovery of neurological function and cognitive function,improve prognosis,reduce the occurrence of complications,and have certain clinical application value.关键词
颅骨缺损/去骨瓣减压术/早期/颅骨修补术/脑血流速度/神经功能/认知功能/预后情况Key words
Skull defect/Decompressive craniectomy/Early/Cranioplasty/Cerebral blood flow velocity/Neurological function/Cognitive function/Prognostic situation分类
医药卫生
