摘要
Abstract
Objective:To investigate the efficacy of Tirofiban and Clopidogrel and Aspirin in combined with Xuesaitong Injection the treatment of patients with acute progressive cerebral infarction(APCI)after thrombolytic time window.Methods:Data of 76 APCI patients after thrombolysis time window treated in Ju County Traditional Chinese Medicine Hospital from January 2022 to January 2024 were retrospectively analyzed.According to different treatment methods,they were divided into a control group and a study group,with 38 cases in each group.Both groups received conventional therapy.On this basis,the control group was treated with Tirofiban,Clopidogrel and Aspirin,and the study group was treated with was used Xuesaitong Injection on the basis of control group.Both groups were treated continuously for 14 days.The clinical efficacy,adverse reactions,coagulation function and nerve function of the two groups were compared.Results:The total effective rate of the study group was 94.74%,which was higher than 78.95%of the control group,the difference was statistically significant(P<0.05).After treatment,the National Institute of Health stroke scale of the study group was(13.11±1.01)points,which was lower than(19.34±1.32)points of the control group,and the difference was statistically significant(P<0.05).After treatment,the prothrombin time and activated partial thromboplastin time of the study group were(11.47±1.55)s and(27.11±2.68)s,respectively,which were longer than(10.74±1.36)s and(25.79±2.29)s of the control group,and the differences were statistically significant(P<0.05).The incidence of adverse reactions in the study group was 13.16%,compared with 7.89%in the control group,the difference was not statistically significant(P>0.05).Conclusion:For APCI patients after thrombolysis time window,Tirofiban,Clopidogrel and Aspirin combined with Xuesaitong Injection can show significant effects,which can not only optimize the coagulation function,accelerate the rehabilitation process of neurological function,but also have a high safety.关键词
急性进展性脑梗死/替罗非班/氯吡格雷/阿司匹林/神经功能/血塞通注射液Key words
Acute progressive cerebral infarction/Tilofiban/Clopidogrel/Aspirin/Neurological function/Xuesaitong Injection分类
医药卫生
