中国伤残医学2024，Vol.32Issue(24)：109-113,5.DOI:10.13214/j.cnki.cjotadm.2024.024.026
钆特酸葡胺在脑转移瘤患者MRI增强扫描检查中的应用效果及其安全性研究
Efficacy and Safety of Gadoteric Acid Meglumine Salt in Enhanced MRI Scanning Examination of Patients with Brain Metastases
摘要
Abstract
Objective:To evaluate the efficacy and safety of gadoteric acid meglumine salt in enhanced magnetic resonance imaging(MRI)scanning in patients with brain metastases.Methods:Data of 60 patients with brain metastases admitted to Chengdu Wenjiang District People's Hospital from January 2022 to July 2024 were retrospectively analyzed.According to different types of contrast agents,they were divided into a control group and a study group,with 30 cases in each group.The control group was treated with gadobenate dimeglumine,an ionic linear gadolinium contrast agent,and the study group was treated with gadoteric acid meglumine salt,an ionic large ring gadolinium contrast agent.The diagnostic efficacy and safety of MRI enhanced scanning with different contrast agents in MRI of brain metastases were compared.Results:The relative signal intensity ratio of the real part of the lesion at the timely enhancement and delayed enhancement in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).The increase ratio of signal intensity in the dentate nucleus or pallidum of cerebellum in the study group was lower than that in the control group,and the differences were statistically significant(P<0.05).The incidence of adverse events in the study group was 3.33%,which was lower than 20.00%in the control group;the incidence of adverse reactions in the research group was 3.33%,which was lower than the control group's 26.67%,and the differences were statistically significant(P<0.05).Conclusion:Gadoteric acid meglumine salt,a large ring gadolinium contrast agent,has a significant ability to detect brain metastases with better safety.关键词
脑转移瘤/钆特酸葡胺/检出能力/安全性Key words
Brain metastases/Gadoteric acid meglumine salt/Detection ability/Security分类
医药卫生引用本文复制引用
蔡梦杰,张傲,刘亚龙,杜定学..钆特酸葡胺在脑转移瘤患者MRI增强扫描检查中的应用效果及其安全性研究[J].中国伤残医学,2024,32(24):109-113,5.基金项目
四川省医学会(恒瑞)科研基金专项科研课题(2021HR38) （恒瑞）
