实验动物与比较医学2025，Vol.45Issue(1)：96-100,5.DOI:10.12300/j.issn.1674-5817.2024.106
实验动物屏障环境设施安全准入体系建设的探索与实践——以南京大学仙林校区为例
Exploration and Practice of Safe Access System Construction for Barrier Environment Facilities of Laboratory Animals:A Case Study on Xianlin Campus of Nanjing University
摘要
Abstract
Laboratory animals are essential in scientific research and experimental teaching in colleges and universities.Disciplines such as life sciences,medicine,pharmacy,chemistry,and biomedical engineering heavily rely on animal experiments.The standardized barrier environmental facility for laboratory animals provides a fundamental platform for stable,scientific,and reliable animal experiment results.Rigorous access management for such facilities is a vital safeguard for maintaining standardized operations of facilities,controlling the quality and stability of laboratory animals,mitigating pathogen contamination risks among animals and laboratory staff,and preventing biosecurity incidents such as zoonotic disease outbreaks.Taking the small-scale barrier facilities for laboratory rats and mice at Nanjing University's Xianlin Campus,operational since 2019,as an example,this study focuses on the safety access management system of these facilities.Based on five years of operational data and accumulated experience in studying and optimizing the access management system,this study,from the perspectives of management system development and the formulation and implementation of standard operating procedures,reviews five aspects of access management:personnel access,animals access,material access,equipment access,and air circulation control.Furthermore,these aspects are systematically analyzed and summarized to serve as a reference for the construction and management of the laboratory animal facilities in universities,while also contributing to scientific research,public health security,and the well-being of experimental personnel.关键词
实验动物/屏障环境设施/准入管理/生物安全Key words
Laboratory animal/Barrier environmental facility/Access management/Biosafety分类
生物学引用本文复制引用
侯冬霞,铁祚庥,陆勇,南盼盼,鲍洁..实验动物屏障环境设施安全准入体系建设的探索与实践——以南京大学仙林校区为例[J].实验动物与比较医学,2025,45(1):96-100,5.基金项目
南京大学2023年度实验室安全研究课题"实验动物屏障设施的安全准入体系研究"(LSK202302) （LSK202302）
