上海针灸杂志2025，Vol.44Issue(3)：331-336,6.DOI:10.13460/j.issn.1005-0957.2024.13.4018
电针联合宫腔灌注对薄型子宫内膜胚胎移植妊娠结局和焦虑状态的影响
Effect of electroacupuncture combined with intrauterine infusion on pregnancy outcome and anxiety state of embryo transfer with thin endometrium
摘要
Abstract
Objective To observe the effects of electroacupuncture combined with intrauterine infusion of granulocyte-colony stimulating factor(G-CSF)on pregnancy outcome and anxiety state of patients with thin endometrium undergoing frozen-thawed embryo transfer(FET).Method A total of 102 patients with thin endometrium who underwent FET were randomly divided into a study group(54 cases)and a control group(48 cases).The study group was treated with electroacupuncture therapy combined with G-CSF intrauterine infusion,and the control group was treated with G-CSF intrauterine infusion.The endometrial thickness,morphology,hemodynamic parameters and Hamilton anxiety scale(HAMA)scores of the two groups were compared before and after treatment,and the embryo implantation rate,clinical pregnancy rate and early miscarriage rate were followed up.Result After treatment,the endometrial thickness of both groups were higher than those before treatment,and that of the study group was higher than that of the control group,and the differences were statistically significant(P＜0.05).After treatment,the proportion of type A endometrium in the study group was higher than that in the control group,and the difference was statistically significant(P＜0.05).After treatment,the resistance index(RI)of both groups were lower than those before treatment,and that of the study group was lower than that of the control group,and the difference was statistically significant(P＜0.05).After treatment,the vascularization index(VI),flow index(FI)and vascularization blood flow index(VFI)of both groups were higher than those before treatment,and those of the study group were higher than those of the control group,and the difference was statistically significant(P＜0.05).The HAMA scores of both groups were lower than those before treatment,and those of the study group were lower than those of the control group,and the difference was statistically significant(P＜0.05).The embryo implantation rate and clinical pregnancy rate of the study group were higher than those of the control group,and the differences were statistically significant(P＜0.05),while the rate of early miscarriage tended to decrease,but the differences were not statistically significant(P＞0.05).Conclusion Electroacupuncture combined with G-CSF intrauterine infusion can increase the embryo implantation rate and clinical pregnancy rate in patients with thin endometrium who underwent FET,and it can relieve anxiety,and the effect is better than that of G-CSF alone.关键词
电针/宫腔灌注/辅助生殖技术/不孕症/不育,女性/子宫内膜容受性/血液流变学Key words
Electroacupuncture/Intrauterine infusion/Assisted reproductive technology/Infertility/Sterility,female/Endometrial tolerance/Blood rheology分类
医药卫生引用本文复制引用
许婷,曹华斌,庄元..电针联合宫腔灌注对薄型子宫内膜胚胎移植妊娠结局和焦虑状态的影响[J].上海针灸杂志,2025,44(3):331-336,6.基金项目
江西省中医药管理局科技计划课题(2022A211) （2022A211）
江西省卫生健康委科技计划课题(202211101) （202211101）
