世界科学技术-中医药现代化2025，Vol.27Issue(2)：337-345,9.DOI:10.11842/wst.20231219005
温灸神阙穴治疗大学生原发性痛经效果及机制研究
Effect and Mechanism of Warming Moxibustion at Shenque Point in the Treatment of Primary Dysmenorrhea in College Students
摘要
Abstract
Objective This study aims to observe the impact of warm moxibustion on menstrual pain in college students with primary dysmenorrhea and explore its potential mechanism.Methods College students with primary dysmenorrhea were recruited and treated with warm moxibustion at Shenque acupoint for three consecutive menstrual cycles.Healthy subjects were also recruited for comparison.Pain scale,uterine artery hemodynamics,and related inflammatory factors were assessed before and after treatment.Results ①The results of scale study showed that the severity and duration of dysmenorrhea were gradually alleviated with the prolongation of treatment time through the analysis of variance of repeated measurements of the total scores of McGill pain inquiry scale and CMSS dysmenorrhea symptom scale before and after 3 treatments.The results of variance analysis and pairwise comparison of repeated measurements of PRI,VAS and PPI of McGill pain inquiry scale before and after 3 times treatment in warm moxibustion group also showed that each index decreased gradually with the prolongation of treatment time.The comparison of the scores of each item of CMSS scale showed that the severity and duration of low back before treatment were significantly different from those in the healthy group(P<0.001),but the difference was weakened after the third treatment.The severity of vomiting,the duration of vomiting,the severity of diarrhea and the duration of diarrhea were significantly different from those in the healthy group before treatment(P<0.001),but they were still higher than those in the healthy group after the third treatment.but the difference was not statistically significant.②Prior to treatment,PD college students exhibited significantly higher S/D and PI values on both sides compared to healthy subjects,with a statistically significant difference observed for PI on the left side(P<0.001).Following treatment,all aforementioned indexes decreased significantly,particularly PI on the left side which showed a significant difference from pre-treatment levels(P<0.001).③Before treatment,the levels of serum IL-1β,TNF-α,and CRP in PD college students were significantly higher compared to those in the healthy group.The difference in IL-1β level was statistically significant(P<0.001).After treatment,there was a noticeable decrease in the levels of IL-1β,TNF-α,and CRP.Specifically,IL-1β showed a significant reduction(P<0.01),and this time the comparison with the healthy group did not reveal any significant difference in IL-1β levels.Conclusion The application of warm moxibustion at the Shenque acupoint demonstrates a significant improvement in both the dysmenorrhea pain rating index and severity among college students with primary dysmenorrhea,while also alleviating the severity and duration of associated symptoms.These positive effects may be attributed to warm moxibustion's ability to enhance uterine microcirculation in individuals with primary dysmenorrhea,and ameliorating inflammatory conditions.关键词
原发性痛经/温灸/神阙穴/子宫微循环/炎症因子Key words
Primary dysmenorrhea/Warm moxibustion/Shenque acupoint/Uterine microcirculation/Inflammatory factor分类
医药卫生引用本文复制引用
张燕茹,燕晓雯,陈佳鑫,马海燕,王海燕,马英锋,朱向东,李保有,郭建红..温灸神阙穴治疗大学生原发性痛经效果及机制研究[J].世界科学技术-中医药现代化,2025,27(2):337-345,9.基金项目
国家自然科学基金委员会地区科学基金项目(82360967):传统运动联合能量限制调控肠道菌群改善肥胖型糖尿病前期糖脂代谢作用机制研究,负责人:郭建红. （82360967）
