饲料研究2025，Vol.48Issue(2)：104-108,5.DOI:10.13557/j.cnki.issn1002-2813.2025.02.019
百香果多糖对沙门氏菌感染雏鸡肠道免疫的调节作用
Regulatory effects of passion fruit polysaccharides on intestinal immunity in chicks infected with Salmonella
摘要
Abstract
The experiment aimed to investigate the immunomodulatory effect of passion fruit polysaccharides on the intestinal mucosa of Salmonella-infected ephedra chicks.A total of 24 healthy seven-day-old spotted-brown chicks were randomly divided into three groups:A normal control group,an infection control group,and a passion fruit polysaccharide group,with eight replicates in each group and one chicken in each replicate.The passion fruit polysaccharide group was gavaged with a passion fruit polysaccharide solution for five days and then orally infected with Salmonella.After 24 hours of infection,the duodenum was collected for immune marker detection and histological observation of tissue changes.The results showed that compared with the infection control group,passion fruit polysaccharide group significantly increased the levels of immunoglobulin G(IgG)and secretory immunoglobulin A(SIgA)in the duodenal wash fluid(P＜0.05),slightly increased the levels of mucin 2(MUC2)and trefoil factor(TFF),and significantly alleviated the intestinal mucosal epithelial structural damage induced by Salmonella.There were no significant differences in the immune organ index,serum glutathione peroxidase(GSH-Px),and total superoxide dismutase(T-SOD)activities between the normal control group and passion fruit polysaccharide groups(P＞0.05).The study indicates that passion fruit polysaccharides can improve Salmonella-induced enteritis by promoting the secretion of intestinal immunoglobulins.关键词
百香果多糖/沙门氏菌/肠道免疫/免疫球蛋白/肠上皮损伤Key words
passion fruit polysaccharides/Salmonella/intestinal immunity/immunoglobulins/intestinal epithelial injury分类
农业科技引用本文复制引用
申心怡,黎媛媛,王晓霞,黄璟昇,黄康萍,李环,何家康,梁正敏..百香果多糖对沙门氏菌感染雏鸡肠道免疫的调节作用[J].饲料研究,2025,48(2):104-108,5.基金项目
广西重点研发项目(项目编号:桂科AB23026082) （项目编号:桂科AB23026082）
广西科技基地和人才专项项目(项目编号:桂科AD23026289) （项目编号:桂科AD23026289）
广西大学大学生创新创业训练计划项目(项目编号:202310593440) （项目编号:202310593440）
