饲料研究2025，Vol.48Issue(2)：139-143,5.DOI:10.13557/j.cnki.issn1002-2813.2025.02.025
响应面法优化两面针中两种生物碱的超声提取工艺
Optimization of ultrasonic extraction process for two alkaloids in Zanthoxylum nitidum by Box-Behnken response surface method
摘要
Abstract
In order to optimize the extraction process of nitidine chloride and chelerythrine chloride from Zanthoxylum nitidum,based on single-factor experiments,the Box-Behnken response surface method was used to investigate the effects of ultrasonic extraction time,ethanol concentration,and liquid-to-solid ratio on the ultrasonic extraction rates of nitidine chloride and chelerythrine chloride.The results showed that under the conditions of an extraction time of 37.5 minutes,two extractions,an ethanol concentration of 60%,and a liquid-to-material ratio of 20 mL/g,the extraction yields of Zanthoxylum nitidum alkaloid and chelerythrine from Zanthoxylum nitidum were the highest,reaching 0.347%and 0.475%,with fitting rates of 98.6%and 98.9%compared to the predicted values,respectively.The study indicates that this extraction process is stable,reliable,simple,and efficient,suitable for the extraction of nitidine chloride and chelerythrine chloride from Zanthoxylum nitidum,and can provide a reference for further purification and extraction of nitidine chloride and chelerythrine chloride from Zanthoxylum nitidum,as well as for the research of Zanthoxylum nitidum as a natural antibacterial feed and veterinary medicine for poultry and livestock.关键词
两面针/氯化两面针碱/白屈菜红碱/响应面法/超声提取工艺Key words
Zanthoxylum nitidum/nitidine chloride/chelerythrine chloride/response surface method/ultrasonic extraction process分类
农业科技引用本文复制引用
乔丽娅,胡凤云,张占江,胡营,韦筱媚,朱艳霞..响应面法优化两面针中两种生物碱的超声提取工艺[J].饲料研究,2025,48(2):139-143,5.基金项目
广西科技计划项目(项目编号:桂科AB22035068) （项目编号:桂科AB22035068）
广西中医药管理局广西特色药材关键技术研究推广项目(项目编号:GZKJ2314) （项目编号:GZKJ2314）
