生命科学仪器2025，Vol.23Issue(1)：118-120,3.DOI:10.11967/2025230241
人类肿瘤中热休克蛋白家族成员HSPA13的作用及研究进展
The Role And Research Progress of HSPA13 A Member of Heat Shock Protein Family in Human Tumors
万洁 1李晓东 1徐培栋 2马斌林1
作者信息
- 1. 新疆医科大学第三临床医学院(附属肿瘤医院),新疆乌鲁木齐 830000
- 2. 新疆医科大学附属肿瘤医院介入诊疗科,新疆乌鲁木齐 830000
- 折叠
摘要
Abstract
As a highly functional molecular chaperone,Heat shock protein(HSP)can keep the balance between pro-tein synthesis and degradation in cancer cells,so that cancer cells can survive under the continuous stimulation of harsh microenvironment,and it is an indispensable factor in the occurrence and development of cancer.Heat shock protein a member 13(HSPA13)is a member of HSP family.Existing research shows that HSPA13 is overexpressed in most cancer cells,which can promote tumor progression in many ways.With the further exploration of the mechanism of HSPA13 in tumor,HSPA13 has become the target of various cancer treatments.In this paper,the structure and func-tion of HSPA13 and its relationship with human cancer are reviewed.关键词
热休克蛋白/HSPA13/肿瘤/研究进展Key words
Heat shock proteins/HSPA13/Tumour/Research advances分类
医药卫生引用本文复制引用
万洁,李晓东,徐培栋,马斌林..人类肿瘤中热休克蛋白家族成员HSPA13的作用及研究进展[J].生命科学仪器,2025,23(1):118-120,3.
