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Using protein turnover assay to explore the drug mechanism of Carfilzomib

Yonghui Tao Xinyu Ding Caiwei Jia Chengcheng Wang Chuanyin Li

生物化学与生物物理学报(英文版)2025,Vol.57Issue(2):209-222,14.
生物化学与生物物理学报(英文版)2025,Vol.57Issue(2):209-222,14.DOI:10.3724/abbs.2024104

Using protein turnover assay to explore the drug mechanism of Carfilzomib

Using protein turnover assay to explore the drug mechanism of Carfilzomib

Yonghui Tao 1Xinyu Ding 2Caiwei Jia 3Chengcheng Wang 4Chuanyin Li1

作者信息

  • 1. Department of Colorectal Surgery and Oncology(Key Laboratory of Cancer Prevention and Intervention,China National Ministry of Education,Key Laboratory of Molecular Biology in Medical Sciences,Zhejiang Province,China),the Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310009,China||State Key Laboratory of Molecular Biology,Shanghai Institute of Biochemistry and Cell Biology,Center for Excellence in Molecular Cell Science,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Shanghai 200031,China
  • 2. Department of Thoracic Surgery,Shanghai Pulmonary Hospital,Tongji University School of Medicine,Shanghai 200433,China
  • 3. State Key Laboratory of Molecular Biology,Shanghai Institute of Biochemistry and Cell Biology,Center for Excellence in Molecular Cell Science,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Shanghai 200031,China
  • 4. School of Medicine,Guizhou University,Guiyang 550025,China
  • 折叠

摘要

关键词

Carfilzomib/multiple myeloma/profiling/protein homeostasis

Key words

Carfilzomib/multiple myeloma/profiling/protein homeostasis

引用本文复制引用

Yonghui Tao,Xinyu Ding,Caiwei Jia,Chengcheng Wang,Chuanyin Li..Using protein turnover assay to explore the drug mechanism of Carfilzomib[J].生物化学与生物物理学报(英文版),2025,57(2):209-222,14.

基金项目

This work was supported by the grants from the Shanghai Sailing Program(19YF1444700),the National Natural Science Foundation of China(Nos.31900804 and 82304563),the Guizhou Province Science and Technology Foundation([2020]1Y086),and the Science and Technology Foundation of Guizhou Provincial Health Commission(No.gzwkj2022-219). (19YF1444700)

生物化学与生物物理学报(英文版)

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