实用休克杂志（中英文）2024，Vol.8Issue(5)：286-289,4.
急性脑血管病患者甲状腺激素水平的临床分析
Thyroid hormone levels in patients with acute cerebrovascular diseases
摘要
Abstract
Objective Acute cerebrovascular disease is related to changes in pituitary hypotha-lamic neuroendocrine function.This article aims to explore the degree of impact of different acute ce-rebrovascular diseases on thyroid function.Methods 72 patients with acute cerebrovascular disease(within 72 hours of onset)admitted to the hospital from September 2020 to September 2023 were se-lected as the stroke group.The stroke group was further divided into cerebral infarction group and cerebral hemorrhage group.30 patients without cerebrovascular disease or other thyroid function dis-orders admitted during the same period were selected as the control group.Perform NIHSS scoring on all enrolled cases,detect thyroid hormones:triiodothyronine(T3),thyroxine(T4),free triiodothy-ronine(FT3),free thyroxine(FT4),thyroid stimulating hormone(TSH),perform t-tests and com-parisons,P＜0.05 indicates a statistically significant difference.Results The stroke group and the control group had a significant difference of two independent samples,NIHSS[(11.38±7.47)vs.(0.0±0.00),P＜0.05]、T3[(1.20±0.36)nmol/L vs.(1.48±0.27)nmol/L、FT3(3.60±0.92)pmol/L vs.(4.23±0.51)pmol/L,P＜0.05].Two independent samples of cerebral infarc-tion group and the control group significant difference,NIHSS[(11.51±7.68)vs.(0.0±0.00),P＜0.05]、T3[(1.26±0.36)nmol/L vs.(1.48±0.27)nmol/L、FT3(3.70±0.84)pmol/L vs.(4.23±0.51)pmol/L,P＜0.05].Two independent samples of cerebral hemorrhage and con-trol groups were significantly different,NIHSS[(10.78±6.67)vs.(0.0±0.00),P＜0.05]、T3[(0.94±0.29)nmol/L vs.(1.48±0.27)nmol/L、FT3(2.79±0.83)pmol/L vs.(4.23±0.51)pmol/L,P＜0.05].Two independent samples of cerebral hemorrhage and cerebral infarc-tion were significantly different,while the NIHSS was no significant,T3[(0.94±0.29)nmol/L vs.(1.26±0.36)nmol/L、FT3(2.79±0.83)pmol/L vs.(3.78±0.84)pmol/L,P＜0.05].Conclusions The reduction of FT3 and T3 was mainly observed in the stroke group,cerebral infarc-tion group,and cerebral hemorrhage group compared with the control group,which has certain guid-ing significance for judging the severity and prognosis of stroke.The t-test was conducted between the cerebral infarction group and the cerebral hemorrhage group,and there was no significant difference in NIHSS.There were also significant differences in T3 and FT3,and cerebral hemorrhage had a greater impact on T3 and FT3(P＜0.05).关键词
急性脑血管病/三碘甲状腺原氨酸/甲状腺素/游离三碘甲状腺原氨酸/游离甲状腺素Key words
Acute cerebrovascular disease/Triiodothyronine/Thyroxine/Free triiodothyro-nine/Free thyroxine引用本文复制引用
吴敏,孙婷,彭敏轩,唐姣琪,刘安民..急性脑血管病患者甲状腺激素水平的临床分析[J].实用休克杂志（中英文）,2024,8(5):286-289,4.基金项目
湖南省自然科技计划项目(项目编号:2024JJ7669) （项目编号:2024JJ7669）
