实用休克杂志（中英文）2024，Vol.8Issue(5)：309-312,4.
肠瘘并发腹腔感染患者的致病菌类别临床分析
Clinical analysis of pathogenic bacterial infection in patients with intestinal fistula complicated with ab-dominal infection
摘要
Abstract
Objective Through the clinical analysis of the infection situation,pathogen strain distribution and drug resistance of patients with intestinal fistula complicated by peritoneal infection with positive bacterial culture,the clinical characteristics,strain distribution and drug resistance of in-testinal fistula patients were summarized,so as to better guide the accurate use of antibiotics in early clinical stage.Methods The case data of patients with postoperative intestinal fistula complicated with peritoneal infection and positive bacterial culture in ascites or drainage fluid admitted to Hunan People's Hospital from January 2022 to June 2024 were retrospectively analyzed.The bacterial species composition ratio and drug resistance rate of thepathogenic bacteria were calculated,and the infection characteristics and drug resistance status were analyzed.Results Klebsiella pneumoniae and Esche-richia coli were the main pathogens detected,accounting for 25％and 17.3％respectively,followed by Enterococcus faecium,accounting for 15.4％,Candida albicans accounted for 13.5％.Klebsiella pneumoniae and Escherichia coli were sensitive to carbapenems and had high resistance to quinolones.Enterococcus faecium was sensitive to vancomycin,linezolid and other drugs,and had high resistance rate to quinolones,clindamycin and erythromycin.The detection rate of Candida albicans was signifi-cantly higher than before,and it was sensitive to common antifungal drugs.Conclusions The detec-tion rate of drug-resistant bacteria and fungi in the pathogenic bacteria culture of patients with intesti-nal fistula complicated with abdominal infection was higher than before.Rational application of antibi-otics and timely control of infection sources are the key to the treatment of intestinal fistula complicat-ed with abdominal infection.关键词
肠瘘/腹腔感染/耐药菌/合理用药Key words
Gastrointestinal fistula/Abdominal infection/Drug-resistance pathogens/Ra-tional use of antibiotics引用本文复制引用
李军,王励之,王江,陈超武..肠瘘并发腹腔感染患者的致病菌类别临床分析[J].实用休克杂志（中英文）,2024,8(5):309-312,4.基金项目
湖南省自然科学基金项目(项目编号:2019JJ50321) （项目编号:2019JJ50321）
