天津中医药大学学报2025，Vol.44Issue(2)：111-117,7.DOI:10.11656/j.issn.1673-9043.2025.02.04
499例甲型流行性感冒轻症中医证候分析
Traditional Chinese medicine syndrome analysis of 499 cases of mild influenza A
摘要
Abstract
[Objective]To explore the Chinese medicine evidence for mild influenza A illness using latent class analysis.[Methods]Information on four consultations of patients with mild influenza A was collected,and SPSS 25.0 and Mplus 8.3 software were used to analyze the frequency of descriptive data,extract the items with greater relevance to mild influenza A by factor analysis,and then perform potential category analysis to summarize the main Chinese medicine symptoms,and perform logistic regression analysis on the factors that might affect the distribution of Chinese medicine symptoms.[Results]A total of 499 patients were included,and the frequency of symptoms,in descending order,were cough,muscle pain,fatigue,red throat,and severe headache,etc..Twenty-two symptomatic items of high relevance to the mild symptoms of influenza A were extracted by factor analysis,and four types of traditional Chinese medicine symptom manifestation combinations were derived from the analysis of potential categories,namely,the wind-cool bundle of surface symptoms(25.1％),the wind-heat offending the wei and dampness symptoms(44.5％),the surface cold and internal heat symptoms(20％)(10.4％)[1].Logistic regression analysis showed that with the wind-heat offending the guard and entrapping dampness syndrome as the reference,the likelihood of manifesting the wind-cold bundled surface syndrome for a disease duration of ≤ 1 day was 1.955 times higher than that of a disease duration of＞2 days(OR=1.955,95％CI=1.024-3.732,P=0.042),and that the likelihood of manifesting the wind-cold bundled surface syndrome and the epidemiological-cold and internal-heat syndrome without the use of medication prior to the visit was higher than that of using antidotes prior to the visit,respectively were 0.267 times more likely(OR=0.267,95％CI=0.087-0.822,P=0.021)and 0.281 times more likely(OR=0.281,95％CI=0.081-0.975,P=0.046),respectively than those who had used antiviral medication prior to the consultation.[Conclusion]Most of the mild cases of influenza A were wind-heat against the guard and dampness syndrome,followed by wind-cold bundle surface syndrome,surface-cold and internal-heat syndrome,and wind-heat against the guard.The short course of disease is mainly due to exterior syndrome of wind-cold bundle,and the syndrome of wind-heat invading wei and dampness is the main one without antiviral drugs.关键词
甲型流行性感冒/中医证候/潜在类别分析/Logistic回归分析Key words
influenza A/syndrome of traditional Chinese medicine/latent category analysis/logistic regression analysis分类
临床医学引用本文复制引用
赵晶敏,李桂伟,苏日娜,张思涵,赵启亮,张慧琪,杜晶辉,刘旻,孙宏源,孙昕..499例甲型流行性感冒轻症中医证候分析[J].天津中医药大学学报,2025,44(2):111-117,7.基金项目
国家重点研发计划课题项目(2018YFC1707503) （2018YFC1707503）
天津市卫生健康科技人才培育项目(KJ20205) （KJ20205）
天津中医药大学教育教学改革研究项目(2023YJY036) （2023YJY036）
孙昕天津市名中医传承工作室项目 （）
李桂伟天津市名中医传承工作室项目. （）
