妇儿健康导刊2025，Vol.4Issue(4)：31-34,55,5.DOI:10.3969/j.issn.2097-115X.2025.04.004
宫颈癌患者血清Gal-9水平变化及其与临床病理特征的关系分析
Analysis of change of serum Gal-9 level in patients with cervical cancer and its correlation with clinical pathological characteristics
陈海燕1
作者信息
- 1. 山东省公共卫生临床中心病理科,山东 济南 250102
- 折叠
摘要
Abstract
Objective To analyze the change of serum Gal-9 level in patients with cervical cancer and its correlation with clinical pathological characteristics.Methods A total of 62 patients with cervical cancer admitted to Shandong Public Health Clinical Center from April 2021 to October 2023 were selected as the cervical cancer group,54 patients with cervical squamous intraepithelial lesion(SIL)were selected as the SIL group,and 46 patients with chronic cervicitis were selected as the chronic cervicitis group.The level of Gal-9 was detected and compared among the three groups.Cervical cancer patients were divided into high expression group and low expression group according to the median level of Gal-9,and the clinical pathological characteristics of the two groups were compared.Results The median level of Gal-9 in cervical cancer group was higher than that in SIL group and chronic cervicitis group(P<0.05),and the median level of Gal-9 in SIL group was higher than that in chronic cervicitis group(P<0.05).There were significant differences in lymph node metastasis and pathological grade between the low expression group and the high expression group(P<0.05).There were no significant differences in age,depth of invasion,pathological type,tumor size,clinical stage,parametrial involvement,tumor diameter,human papilloma virus infection between low expression group and high expression group(P>0.05).Conclusion Serum Gal-9 level increases with the aggravation of cervical lesions,and is related to lymph node metastasis and pathological grade.关键词
宫颈癌/血清Gal-9/临床病理特征/淋巴转移/病理分级Key words
Cervical cancer/Serum Gal-9/Clinical pathological characteristic/Lymph node metastasis/Pathological grade分类
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陈海燕..宫颈癌患者血清Gal-9水平变化及其与临床病理特征的关系分析[J].妇儿健康导刊,2025,4(4):31-34,55,5.
