妇儿健康导刊2025，Vol.4Issue(4)：193-198,6.DOI:10.3969/j.issn.2097-115X.2025.04.042
中性粒细胞与淋巴细胞比值、中性粒细胞与血清白蛋白比值对非紫绀型先天性心脏病术后拔管时机的评估价值
Value of neutrophil-to-lymphocyte ratio and neutrophil-to-serum albumin ratio in assessing the timing of postoperative extubation in noncyanotic congenital heart disease
闫丽伟 1陈志刚 1吴振宇2
作者信息
- 1. 新乡医学院第一附属医院,河南 新乡 453100
- 2. 河南省胸科医院心外科三病区,河南 郑州 450000
- 折叠
摘要
Abstract
Objective To explore the evaluation value of neutrophil-to-lymphocyte ratio(NLR)and neutrophil-to-serum albumin ratio(NAR)in assessing the timing of postoperative extubation in noncyanotic congenital heart disease(CHD).Methods Two hundred and twenty children with noncyanotic CHD who underwent endocardial direct vision surgery under extracorporeal circulation in Henan Provincial Chest Hospital from June 2021 to June 2023 were selected as the study subjects,and those who were unsuccessful to extubate within 72 hours after CHD surgery or who were re-mechanically ventilated within 24 hours after extubation were included in the late extubation group,and vice versa in the early extubation group.The clinical data,NLR and NAR,and clinical outcomes of the two groups were compared to analyze the factors influencing the timing of postoperative extubation in noncyanotic CHD,and the receiver operating characteristic curve of NLR and NAR was plotted to analyze the value of their assessment on the timing of postoperative extubation in noncyanotic CHD.Results There were 24 cases(10.91%)in the late extubation group and 196 cases(89.09%)in the early extubation group.NLR and NAR in the late extubation group were higher than those in the early extubation group,and the differences were statistically significant(P<0.05).The duration of mechanical ventilation,intensive care unit stay,and hospitalization days in the late extubation group were longer than those in the early extubation group(P<0.05).Multifactorial logistic regression analysis showed that both NLR and NAR were influential factors in the timing of postoperative extubation in noncyanotic CHD(P<0.05).The area under the curve of NLR combined with NAR for assessing the timing of postoperative extubation in noncyanotic CHD was 0.859,with a sensitivity of 79.17%and a specificity of 80.10%.Conclusion NLR and NAR are valuable in assessing the timing of postoperative extubation in noncyanotic CHD and can inform clinical decision making.关键词
非紫绀型先天性心脏病/中性粒细胞与淋巴细胞比值/中性粒细胞与血清白蛋白比值/术后拔管时机Key words
Noncyanotic congenital heart disease/Neutrophil-to-lymphocyte ratio/Neutrophil-to-serum albumin ratio/Timing of postoperative extubation分类
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闫丽伟,陈志刚,吴振宇..中性粒细胞与淋巴细胞比值、中性粒细胞与血清白蛋白比值对非紫绀型先天性心脏病术后拔管时机的评估价值[J].妇儿健康导刊,2025,4(4):193-198,6.
