外科理论与实践2024，Vol.29Issue(6)：510-517,8.DOI:10.16139/j.1007-9610.2024.06.09
影响老年病人全身麻醉非心脏手术术后谵妄发生的因素
Risk factors of postoperative delirium in elderly patients undergoing noncardiac surgery under general anesthesia
摘要
Abstract
Objective To investigate the incidence and related factors of postoperative delirium in elderly patients undergoing elective noncardiac surgery under general anesthesia.Methods Elderly patients aged≥65 years old undergoing non-cardiac surgery under general anesthesia from December 31,2017 to December 31,2018 were retrospectively analyzed.The patients were divided into delirium group and control group according to whether delirium occurred after surgery.Paired t test was used to compare the laboratory test results between the delirium group and the control group.Logistic regression analysis was used to identify the independent risk factors for delirium after non-cardiac surgery in elderly patients.Results A total of 1 072 elderly patients undergoing elective non-cardiac surgery were enrolled in this study.Delirium occurred in 60 patients,and the incidence of delirium was 5.6%.Multivariate Logistic regression analysis showed that postoperative prothrombin time(PT),preoperative blood glucose,preoperative activated partial thromboplastin time(APTT)and postoperative C-reactive protein(CRP)were independent risk factors for delirium after non-cardiac surgery in elderly patients.Conclusions Postoperative PT,preoperative blood glucose,preoperative APTT and postoperative CRP are independent risk factors for POD in elderly patients undergoing non-cardiac surgery.关键词
谵妄/老年/全身麻醉/非心脏手术/危险因素Key words
Delirium/Old population/General anesthesia/Non-cardiac surgery/Risk factor分类
医药卫生引用本文复制引用
吴昕菀,李响,郑旻嘉,姚俊岩..影响老年病人全身麻醉非心脏手术术后谵妄发生的因素[J].外科理论与实践,2024,29(6):510-517,8.基金项目
国家自然科学基金(81771269) （81771269）
