摘要
Abstract
Purpose:To investigate the clinical and imaging characteristics of retinal neovascularization of the optic disc(NVD)and/or elsewhere in the retina(retinal neovascularization elsewhere,NVE)in eyes with Behçet's uveitis(BU).Methods:This retrospective analysis reviewed the clinical data and fundus imaging findings of patients diagnosed with BU complicated by NVD and/or NVE from January 2022 to September 2024.Imaging modalities included fundus photography,fluorescein fundus angiography(FFA),optical coherence tomography(OCT),and OCT angiography(OCTA).The study analyzed the correlation between the areas of NVD and/or NVE and the modified posterior segment inflammation scores,as well as retinal vascular leakage scores of the affected eyes.Results:The study included 27 patients(30 eyes)with an average age of 27.70±12.58 years and a gender ratio of approximately 1:1.Bilateral NVD and/or NVE was observed in three patients(11%);25 eyes(83%)had NVD,of which 17 eyes(57%)had only NVD and 8 eyes(27%)had both NVD and NVE.Two eyes(7%)showed areas of retinal non-perfusion,and seven eyes(23%)had concurrent vitreous hemorrhage.The average score for posterior segment inflammation on FFA was 20.93±4.37,and the average score for vascular leakage was 7.57±1.25.There was a significant positive correlation between the area of NVD and/or NVE and both the inflammation score(rs=0.403,P=0.027)and the vascular leakage score(rs=0.518,P=0.003).FFA and OCTA showed perfect agreement in detecting NVD and NVE(κ=1.0).Conclusion:NVD and/or NVE in BU are not uncommon and are predominantly presented as NVD,mostly not associated with retinal non-perfusion,likely induced by inflammatory factors related to BU.关键词
白塞病性葡萄膜炎/视网膜新生血管/视盘新生血管/多模式影像/炎症Key words
Behçet's uveitis/retinal neovascularization/neovascularization of the optic disc/multimodal imaging/inflammation分类
临床医学
