眼科学报2025，Vol.40Issue(2)：171-178,8.DOI:10.12419/24102203
急性渗出性多形性卵黄样黄斑病变临床研究进展
Clinical research progress on acute exudative polymorphous vitelliform maculopathy
摘要
Abstract
Acute Exudative Polymorphous Vitelliform Maculopathy(AEPVM)is a clinically rare fundus disease characterized primarily by neurosensory detachment in the macular area and accumulation of vitelliform material in the posterior pole.The exact cause is unclear and may be related to systemic infections,autoimmune responses,or paraneoplastic syndromes.Clinical manifestations usually include mild vision loss or photophobia,and yellow-white deposits can be seen in the posterior pole of the fundus,exhibiting relatively higher autofluorescence in spontaneous fluorescence.Fundus fluorescein angiography typically does not show leakage of fluorescein in the lesion area.Optical coherence tomography(OCT)examination can reveal thickening of the ellipsoid zone and cystic changes within the neurosensory layer.Currently,there is no explicit treatment plan.This article reviews the clinical presentation,imaging characteristics,diagnosis and differential diagnosis,pathogenesis,and treatment-related research progress of acute exudative polymorphous vitelliform maculopathy.In summary,the natural course of acute exudative polymorphous vitelliform maculopathy is complex and diverse,and its diagnosis and differential diagnosis remain challenging.A deeper understanding of the clinical presentations and imaging characteristics of acute exudative polymorphous vitelliform maculopathy will facilitate further research and exploration to clarify its pathological mechanisms and identify effective treatment methods in the future.关键词
急性渗出性多形性卵黄样黄斑病变/卵黄样病变/视网膜神经上皮脱离Key words
acute exudative polymorphous vitelliform maculopathy(AEPVM)/yellow-white deposits/neurosensory detachment/vitellum分类
临床医学引用本文复制引用
蒋莉,杨明明..急性渗出性多形性卵黄样黄斑病变临床研究进展[J].眼科学报,2025,40(2):171-178,8.基金项目
深圳市科技创新委员会基础研究面上项目(JCYJ20230807111900002).This work was supported by Shenzhen Science and Technology Innovation Commission,Shenzhen Natural Science Foundation Basic Research Top Project,China(JCYJ20230807111900002). （JCYJ20230807111900002）
