摘要
Abstract
Objective To analyze the application value of contrast-enhanced ultrasound combined with elastography in breast imaging report and data system(BI-RADS)4a nodule biopsy.Methods 250 patients with highly suspected BI-RADS 4a breast nodules admitted to our hospital from January 2023 December 2024 were selected and given contrast-enhanced ultrasound and elastography.Taking pathological biopsy as the gold standard,the clinical diagnostic value of single and combined examination of contrast-enhanced ultrasound and elastography was analyzed.Results Pathological biopsy results showed that among 250 patients with highly suspected BI-RADS 4a breast nodules,120 were benign(benign group)and 130 were malignant(malignant group).Contrast-enhanced ultrasound results showed that 148 were benign and 102 were malignant,with the sensitivity of 59.23％,the specificity of 79.17％,the accuracy of 68.80％,the misdiagnosis rate of 20.83％,and the missed diagnosis rate of 40.77％.Elastography results showed that 144 were benign and 106 were malignant,with the sensitivity of 64.62％,the specificity of 81.67％,the accuracy of 72.80％,the misdiagnosis rate of 18.33％,and the missed diagnosis rate of 35.38％.Contrast-enhanced ultrasound combined with elastography results showed that 124 were benign and 126 were malignant,with the sensitivity of 93.08％,the specificity of 95.83％,the accuracy of 94.40％,the misdiagnosis rate of 4.17％,and the missed diagnosis rate of 6.92％.The sensitivity,specificity,and accuracy of contrast-enhanced ultrasound combined with elastography were significantly higher than those of single examination,and the misdiagnosis rate and missed diagnosis rate were significantly lower than those of single examination(P＜0.05).The ultrasound contrast scores,tumor diameter,BI-RADS score,resistance index,pulsatility index,elastic modulus values(mean,variance,and maximum),and the ratio of breast tumors to the average low-fat elasticity of the same layer in the malignant group were significantly higher than those in the benign group(P＜0.05).Conclusions Contrast-enhanced ultrasound combined with elastography for patients with BI-RADS 4a breast nodules has higher clinical diagnostic value than single contrast-enhanced ultrasound or elastography.关键词
乳腺影像报告和数据系统/4a类乳腺结节/超声造影/弹性成像/诊断价值Key words
Breast imaging report and data system/4a breast nodule/Contrast-enhanced ultrasound/Elastography/Diagnostic value分类
临床医学
