烟台大学学报（自然科学与工程版）2025，Vol.38Issue(1)：17-29,13.DOI:10.13951/j.cnki.37-1213/n.230707
史氏背尖贝(Nipponacmea schrenckii)响应镉胁迫的机制
Mechanism of Nipponacmea schrenckii in Response to Cadmium Stress
摘要
Abstract
The RNA-Seq analysis method is applied to investigate the behavioral patterns of Nipponacmea schrenckii in response to Cd2+stress,and to compare the changes in gene expression levels at different Cd2+concentrations(0,0.01,1.0,and 10.0 mg/L).A total of 261 922 unigenes are assembled,and 32.30％of them are annotated in seven commonly used databases.Based on NR annotation,N.schrenckii shares a high degree of homology with Lottia gigantea.A total of 2021 differentially expressed genes(DEGs)are identified in response to Cd2+stress,and 238 of these genes have higher expression levels with the increasing the Cd2+concentration.The CTSL,GST,and GSTO1 genes are found to be relatively sensitive to changes in Cd2+concentration and could be potential bio-marker genes for marine Cd2+pollution.关键词
史氏背尖贝/RNA-Seq/海洋污染/镉污染Key words
Nipponacmea schrenckii/RNA-Seq/marine pollution/cadmium pollution分类
生物学引用本文复制引用
薛浩,王成红,王丽君,刘秀梅,邢志凯,王爽,王绪敏,曲江勇..史氏背尖贝(Nipponacmea schrenckii)响应镉胁迫的机制[J].烟台大学学报（自然科学与工程版）,2025,38(1):17-29,13.基金项目
山东省重点研发计划(重大科技创新工程)(2021CXGC011306). （重大科技创新工程）
