医学信息2025，Vol.38Issue(4)：171-175,181,6.DOI:10.3969/j.issn.1006-1959.2025.04.033
非酒精性脂肪性肝病与肠道菌群代谢物的关系研究现状
Research Status of the Relationship Between Nonalcoholic Fatty Liver Disease and Intestinal Flora Metabolites
摘要
Abstract
In recent years,nonalcoholic fatty liver disease(NAFLD)has become a global public health problem that endangers human health.The related research of intestinal flora has become an extremely important hot field in clinical medicine and life science research.A growing number of studies have shown that intestinal flora plays an important role in the metabolism of the body.Some intestinal flora metabolites such as butyric acid can improve the body's metabolic disorders by improving the intestinal barrier,reducing insulin resistance,improving steatosis,and reducing inflammation.LPS and other pathogenic factors may cause the body's inflammatory response,aggravate insulin resistance,oxidative stress and lipid metabolism disorders,and then induce NAFLD.This article mainly expounds the correlation between common intestinal flora metabolites and NAFLD-related phenotypes of metabolic diseases,aiming to provide a detailed reference for revealing the relationship between intestinal flora and NAFLD.关键词
非酒精性脂肪性肝病/代谢性疾病/菌群代谢物/肠道菌群Key words
Nonalcoholic fatty liver disease/Metabolic diseases/Microbial metabolites/Gut microbiota分类
医药卫生引用本文复制引用
李梦瑶,伍晓然,徐秋容,王吉,文利新..非酒精性脂肪性肝病与肠道菌群代谢物的关系研究现状[J].医学信息,2025,38(4):171-175,181,6.基金项目
国家自然科学基金面上项目(编号:32373079) （编号:32373079）
