医学信息2025，Vol.38Issue(4)：182-187,6.DOI:10.3969/j.issn.1006-1959.2025.04.035
甲磺酸萘莫司他在ICU高出血风险患者连续性血液净化中的应用
Application of Nafamostat Mesylate in Continuous Blood Purification for ICU Patients with High Bleeding Risk
摘要
Abstract
Anticoagulant drugs play an important role in continuous blood purification(CBP).At present,the commonly used traditional anticoagulant drugs include heparin,low molecular weight heparin,citric acid,etc.These drugs have corresponding complications and contraindications.In ICU,in the face of patients with high risk of bleeding,especially with liver dysfunction and hyperlactacidemia,the above anticoagulant drugs may have limitations.Nafamostat mesilate has the characteristics of safety and effectiveness,and can be used as the first choice of anticoagulation for continuous blood purification in patients with high risk of bleeding.However,the monitoring indicators used by nafamostat and its advantages and limitations still need more clinical trials to verify.This article mainly summarizes the application of nafamostat as an anticoagulant drug for continuous blood purification in patients with high bleeding risk,and provides reference for clinical decision-making.关键词
甲磺酸萘莫司他/抗凝/高出血风险/连续性血液净化Key words
Nafamostat mesylate/Anticoagulant/High bleeding risk/Continuous blood purification分类
医药卫生引用本文复制引用
任彦文,向淑麟..甲磺酸萘莫司他在ICU高出血风险患者连续性血液净化中的应用[J].医学信息,2025,38(4):182-187,6.基金项目
广西医疗卫生适宜技术开发与推广应用项目(编号:S2022016) （编号:S2022016）
