中风与神经疾病杂志2025，Vol.42Issue(2)：99-103,5.DOI:10.19845/j.cnki.zfysjjbzz.2025.0020
帕金森病、原发性震颤和神经元核内包涵体病的震颤特点
Characteristics of tremor in Parkinson disease,essential tremor,and neuronal intranuclear inclusion disease
冯焕焕 1宁金环 2林仲希 1刘婧玥 3许保磊 3许二赫1
作者信息
- 1. 首都医科大学宣武医院神经内科,北京 100053
- 2. 厦门医学院附属第二医院神经内科,福建 厦门 361021
- 3. 首都医科大学宣武医院国家老年疾病临床医学研究中心,北京 100053
- 折叠
摘要
Abstract
Objective To investigate the characteristics of tremor in Parkinson disease(PD),essential tremor(ET),and neuronal intranuclear inclusion disease(NIID).Methods The surface electromyography(sEMG)data of both upper limbs were collected from 73 patients with tremor(30 patients in PD group,23 in ET group,and 20 in NIID group),and the a power spectral analysis was used to investigate frequency characteristics.A one-way analysis of variance and the chi-square test were used for comparison of electrophysiological parameters on sEMG between the three groups.Results The ET group had a higher tremor frequency than the PD group(F=41.86,P<0.01),while the PD group had a higher tremor frequency than the NIID group in resting state(F=41.86,P=0.002)and in postural state(F=41.86,P=0.011).The PD group had a higher proportion of patients with alternating contractions than the NIID group in resting state(χ2=5.70,P=0.017)and in postural state(χ2=7.24,P=0.007),as well as a higher proportion of such patients than the ET group(χ2=9.67,P=0.002).The PD group also had a higher proportion of patients with harmonic resonances than the NIID group in resting state(χ2=4.64,P=0.031)and in postural state(χ2=7.73,P=0.005),as well as a higher propor-tion of such patients than the ET group(χ2=6.52,P=0.011).Conclusion The highest tremor frequency is observed in ET,while the lowest tremor frequency is observed in NIID;patients with PD have a higher proportion of individuals with alternating contractions or harmonic resonances than patients with NIID and ET.关键词
帕金森病/原发性震颤/神经元核内包涵体病/震颤Key words
Parkinson disease/Essential tremor/Neuronal intranuclear inclusion disease/Tremor分类
临床医学引用本文复制引用
冯焕焕,宁金环,林仲希,刘婧玥,许保磊,许二赫..帕金森病、原发性震颤和神经元核内包涵体病的震颤特点[J].中风与神经疾病杂志,2025,42(2):99-103,5.
