中国当代儿科杂志2025，Vol.27Issue(3)：286-292,7.DOI:10.7499/j.issn.1008-8830.2409030
容量保证的高频振荡通气对呼吸窘迫综合征早产儿的
Efficacy of volume-guaranteed high-frequency oscillatory ventilation in preterm infants with respiratory distress syndrome and its impact on cerebral blood flow in the middle cerebral artery
王月怡 1魏雪旭 1尹海伟 1朱洪斌1
作者信息
- 1. 秦皇岛市妇幼保健院新生儿科,河北 秦皇岛 066000
- 折叠
摘要
Abstract
Objective To investigate the efficacy of volume-guaranteed high-frequency oscillatory ventilation(HFOV-VG)in preterm infants with respiratory distress syndrome(RDS)and its impact on blood flow in the middle cerebral artery(MCA).Methods A prospective study was conducted on 120 preterm infants with RDS who were admitted to the Department of Neonatology at Qinhuangdao Maternal and Child Health Hospital from March 2020 to December 2023.According to the mode of ventilation,the infants were divided into two groups:a conventional mechanical ventilation(CMV)group(60 infants)and an HFOV-VG group(60 infants).The two groups were compared in terms of baseline data,MCA hemodynamic parameters,complications,and outcomes.Results Compared with the CMV group,the HFOV-VG group had significantly shorter durations of mechanical ventilation and hospital stay and a significantly higher overall response rate(P<0.05).The HFOV-VG group demonstrated significantly better peak systolic velocity,end-diastolic velocity,and mean flow velocity(P<0.05).The HFOV-VG group also exhibited significantly lower 28-day mortality rates and lower incidence rates of bronchopulmonary dysplasia and intraventricular hemorrhage than the CMV group(P<0.05).Conclusions HFOV-VG can effectively improve cerebral blood perfusion,reduce cerebrovascular resistance,shorten the durations of mechanical ventilation and hospital stay,and enhance overall treatment efficacy.It has significant advantages in reducing the risk of 28-day mortality,bronchopulmonary dysplasia,and intraventricular hemorrhage in preterm infants with RDS.关键词
呼吸窘迫综合征/容量保证的高频振荡通气/脑血流/疗效/早产儿Key words
Respiratory distress syndrome/Volume-guaranteed high-frequency oscillatory ventilation/Cerebral blood flow/Efficacy/Preterm infant引用本文复制引用
王月怡,魏雪旭,尹海伟,朱洪斌..容量保证的高频振荡通气对呼吸窘迫综合征早产儿的[J].中国当代儿科杂志,2025,27(3):286-292,7.
