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肝细胞癌靶向治疗的现状和进展

陈志文 王龙蓉 王鲁

中国临床药理学与治疗学2025,Vol.30Issue(2):171-182,12.
中国临床药理学与治疗学2025,Vol.30Issue(2):171-182,12.DOI:10.12092/j.issn.1009-2501.2025.02.003

肝细胞癌靶向治疗的现状和进展

Current status and progress of targeted therapy for hepatocellular carcinoma

陈志文 1王龙蓉 1王鲁1

作者信息

  • 1. 复旦大学附属肿瘤医院肝脏外科,复旦大学上海医学院肿瘤学系,上海 200032
  • 折叠

摘要

Abstract

Hepatocellular carcinoma,as a com-mon malignant tumor,remains a serious global health problem.Traditional methods such as surgi-cal resection and chemotherapy have limited ef-fects in improving the prognosis of advanced hepa-tocellular carcinoma.With the deepening of re-search into molecular mechanisms,targeted thera-py has become an important direction for the treat-ment of hepatocellular carcinoma.In this review,we summarize the main targeted drugs and associ-ated therapeutic strategies for hepatocellular carci-noma,aiming to provide references and evidence for future related research.

关键词

肝细胞癌/靶向治疗/免疫治疗/联合治疗

Key words

hepatocellular carcinoma/targeted therapies/immunotherapy/combination therapy

分类

临床医学

引用本文复制引用

陈志文,王龙蓉,王鲁..肝细胞癌靶向治疗的现状和进展[J].中国临床药理学与治疗学,2025,30(2):171-182,12.

基金项目

国家自然科学基金(81874182) (81874182)

国家自然科学基金(M-0334) (M-0334)

上海市抗癌协会翱翔计划(SACA-AX202211) (SACA-AX202211)

北京肝胆相照公益基金会(GDXZ-08-02) (GDXZ-08-02)

北京肝胆相照公益基金会(GDXZ-08-14) (GDXZ-08-14)

中国临床药理学与治疗学

OA北大核心

1009-2501

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