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胰腺癌的靶向治疗进展及前沿

杜楠 魏妙艳 徐近

中国临床药理学与治疗学2025,Vol.30Issue(2):183-192,10.
中国临床药理学与治疗学2025,Vol.30Issue(2):183-192,10.DOI:10.12092/j.issn.1009-2501.2025.02.004

胰腺癌的靶向治疗进展及前沿

Advancements and frontiers in targeted therapy for pancreatic cancer

杜楠 1魏妙艳 1徐近1

作者信息

  • 1. 复旦大学附属肿瘤医院胰腺外科,复旦大学上海医学院肿瘤学系,上海市胰腺肿瘤研究所,上海市胰腺肿瘤精准诊疗重点实验室,复旦大学胰腺肿瘤研究所,上海 200032
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摘要

Abstract

The incidence of pancreatic cancer has been increasing each year,and the 5-year survival rate is still around 10%.Diagnosis and treatment strategies are major concerns in the industry.Gene sequencing and multi-omics research have revealed more signal pathways and actionable targets,offer-ing the potential for new targeted therapeutic drugs.However,current drug treatment for pancre-atic cancer still relies mainly on chemotherapy,and targeted therapy strategies are not yet fully devel-oped and require further discussion.As basic and translational research in pancreatic cancer advances and precision medicine develops,it is expected that targeted treatment for pancreatic cancer will be-come more precise and individualized in the future.This article discusses the current progress and fron-tiers of targeted treatment for pancreatic cancer.

关键词

胰腺癌/靶向治疗/化疗

Key words

pancreatic cancer/targeted therapy/chemotherapy

分类

临床医学

引用本文复制引用

杜楠,魏妙艳,徐近..胰腺癌的靶向治疗进展及前沿[J].中国临床药理学与治疗学,2025,30(2):183-192,10.

基金项目

国家自然科学基金面上项目(82072698) (82072698)

复旦大学附属肿瘤医院临床博士后科学基金资助(ZYJH202114) (ZYJH202114)

中国临床药理学与治疗学

OA北大核心

1009-2501

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