中国临床药理学与治疗学2025，Vol.30Issue(2)：222-231,10.DOI:10.12092/j.issn.1009-2501.2025.02.009
注射用益气复脉治疗心力衰竭的证据图谱研究
Evidence map on the treatment of heart failure with Yiqifumai injec-tion
摘要
Abstract
AIM:To display the distribution of evi-dence in the field of Yiqifumai injection treatment for heart failure.METHODS:To retrieve relevant da-tabases such as CBM,CNKI,Wanfang,VIP,Co-chrane Library,PubMed,Embase,and Web of Sci-ence,and search for the China Clinical Trial Regis-try,ClinicalTrials.gov and collect clinical studies,sys-tematic evaluations,and guideline studies on the treatment of heart failure with Yiqifumai injection.The evidence map research method use a table to display the proportion of literature,sample size,co-morbidities,and quality evaluations of systematic evaluations.Use a pie chart to display the propor-tion distribution of research types,a line chart to describe publication trends,and a bubble chart to display the distribution of evidence.RESULTS:The overall number of articles on the treatment of heart failure with Yiqifumai injection is in a steady development stage.Clinical studies are mainly small sample,single center,short-term randomized controlled trials,with a sample size of 60-100 cases and an intervention duration of mostly 14 days.The underlying disease is mainly coronary heart dis-ease.Clinical research evidence tends to support the therapeutic effect of Yiqifumai injection com-bined with conventional Western medicine in im-proving heart failure patients'heart function and quality of life.However,there are also issues such as low overall quality of research,unreasonable clinical trial design,small sample size,incomplete selection of outcome indicators,low international recognition of certain outcome indicators,and lack of reporting on long-term outcomes The overall quality of randomized controlled trials andsystem-atic evaluation methodology is low.CONCLUSION:In the future,more large sample,multicenter clini-cal randomized controlled trials should be conduct-ed to obtain higher-level evidence-based medicine evidence to fully demonstrate the advantages of traditional Chinese medicine treatment,and pro-mote the common development of traditional Chi-nese medicine cardiology and evidence-based med-icine.关键词
注射用益气复脉/心力衰竭/证据图谱/临床研究Key words
Yiqifumai injection/heart failure/evi-dence map/clinical research分类
基础医学引用本文复制引用
吕仕超,王云姣,左一鸣,商洪才..注射用益气复脉治疗心力衰竭的证据图谱研究[J].中国临床药理学与治疗学,2025,30(2):222-231,10.基金项目
中国博士后科学基金面上项目(2022M710473) （2022M710473）
天津市中医药重点领域科研课题(2024002) （2024002）
天津市教委科研计划项目(2023ZD029) （2023ZD029）
苏州工业园区东方华夏心血管健康研究院——力·心中药科研创新基金(2022-CCA-TCM-020) （2022-CCA-TCM-020）
