中国临床医学影像杂志2025，Vol.36Issue(3)：200-204,5.DOI:10.12117/jccmi.2025.03.010
基于直肠彩色多普勒超声特征联合临床指标的列线图鉴别前列腺良恶性病变的价值
The value of nomogram based on rectal color Doppler ultrasound features combined with clinical indicators in identifying benign and malignant prostatic lesions
摘要
Abstract
Objective:To establish a nomogram based on rectal color Doppler ultrasound features combined with clinical indicators and to assess its discriminatory value for benign and malignant prostate lesions.Methods:One hundred patients with prostate nodules who underwent rectal color Doppler ultrasonography and were confirmed by pathology at the Eighth Hospital of Wuhan City from January 2022 to December 2023 were selected for the study,among which 44 cases of prostatic hyperplasia and 56 cases of prostate cancer.The patients were divided into training set(n=70)and validation set(n=30)by random sampling in the ratio of 7∶3 and were further categorized into benign and malignant groups on the basis of pathological findings.The ultrasound characteristics and clinical related indexes of all patients were collected,and the independent influencing factors of benign and malignant prostate lesions were analyzed by univariate and multivariate Logistic regression and a column chart model was constructed,and the diagnostic efficacy of the column chart model was analyzed by using receiver operating characteristic(ROC)curve.Results:There were 31 benign and 39 malignant cases in the training set,respectively,and the benign and malignant groups in the validation set were 13 and 17,respectively.Comparison of age,internal echo of lesions,flow grading,systolic flow velocity(Vs),diastolic flow velocity(Vd),resistance index(RI),and prostate specific antigen(PSA)between the benign and malignant groups in the training set and the validation set showed statistically significant differences(P<0.05).Multifactorial Logistic regression analysis showed that age,internal echogenicity of the lesion,blood flow grading,RI,and PSA were independent influencing factors for benign and malignant prostate lesions(P<0.05).The AUC of the column line graph model constructed based on the above risk factors was 0.903(95%CI:0.824～0.957)with a sensitivity of 87.10%and a specificity of 82.05%in the training set,and 0.887(95%CI:0.755～0.936)with a sensitivity of 84.62%and a specificity of 82.35%in the validation set.Conclusion:Nomograms constructed on the basis of rectal color Doppler ultrasound features combined with clinical indicators have good discriminatory value for benign and malignant prostate lesions.关键词
前列腺肿瘤/超声检查,多普勒,彩色Key words
Prostatic Neoplasms/Ultrasonography,Doppler,Color分类
医药卫生引用本文复制引用
罗珊,宗华,胡运霞,王玲,向新..基于直肠彩色多普勒超声特征联合临床指标的列线图鉴别前列腺良恶性病变的价值[J].中国临床医学影像杂志,2025,36(3):200-204,5.基金项目
新疆维吾尔自治区自然科学基金项目(2021D01A162). （2021D01A162）
