中国临床医学影像杂志2025，Vol.36Issue(3)：209-212,4.DOI:10.12117/jccmi.2025.03.012
18F-FDG PET/CT显像对下肢长骨骨折相关性感染的诊断价值
Diagnostic value of 18F-FDG PET/CT in fracture related infection of lower extremities
摘要
Abstract
Objective:To investigate the 18F-FDG PET/CT features of fracture related infection(FRI)in lower extremities and to increase awareness of the disease.Methods:Retrospective analysis of 18F-FDG PET/CT images of 42 patients who had been confirmed as FRI of lower extremities in Beijing Jishuitan Hospital from May 2019 to October 2022,the 18F-FDG PET/CT metabolic features were analyzed.Results:Eighteen cases were femoral fractures and 24 cases were tibiofibular fractures.In all 42 cases,18F-FDG uptake was increased at the fracture site.Thirty-four cases were shown around the fracture site and 10 cases were shown around the long bone.Sixteen cases were shown at the medullary cavity near the fracture site and 11 cases were shown at the long bone marrow cavity.Twenty cases were shown around internal fixation and 12 cases were shown at the nail path.Sinus was found in 11 cases and abscess was found in 3 cases.The mean maximum standardized uptake value(SUVmax)was 7.34±2.94.The mean SUVmax ratios of infected area to inactive muscle and the normal side were 5.99±2.79 and 3.72±1.91,respectively.All cases were divided into two groups according to the bacterial virulence and there was no significant difference in these three measurements between groups.Conclusion:18F-FDG PET/CT can show the location and extent of infection in FRI of lower extremities and it is not affected by metal fixator.18F-FDG uptake is increased at infected area which could be single or multiple and it is obviously higher than inactive muscles and contralateral side.Sinus and abscess have characteristic features.关键词
骨折/下肢骨/感染/正电子发射断层显像计算机体层摄影术/氟脱氧葡萄糖F18Key words
Fractures/Bones of Lower Extremity/Infections/Positron Emission Tomography Computed Tomography/Fluorodeoxyglucose F18分类
医药卫生引用本文复制引用
韩洁,冯瑾,张连娜,杨芳..18F-FDG PET/CT显像对下肢长骨骨折相关性感染的诊断价值[J].中国临床医学影像杂志,2025,36(3):209-212,4.基金项目
吴阶平医学基金(320.6750.2022-2-42). （320.6750.2022-2-42）
