中国临床医学影像杂志2025，Vol.36Issue(3)：213-217,5.DOI:10.12117/jccmi.2025.03.013
常规超声联合超微血流成像评估血友病性滑膜炎在骨软骨损伤风险预测中的应用价值
The value of conventional ultrasound combined with superb microvascular imaging in assessing hemophilic synovitis for predicting the risk of osteochondral injury
摘要
Abstract
Objective:Using conventional ultrasound and superb microvascular imaging(SMI)to assess hemophilic synovitis,exploring their predictive value for osteochondral injury.Methods:Fifty-seven hemophilia A patients visited our hospital from January 2023 to December 2023,with a total of 155 affected joints enrolled.Conventional ultrasound and synovial SMI examinations were performed on the affected joints.The study analyzed the correlation between clinical data,conventional ultrasound and SMI parameters with osteochondral injury,and compared the differences in clinical data,conventional ultrasound characteristics,and SMI parameters between joints with osteochondral injury and those without.The independent risk factors for osteochondral injury were analyzed,and the receiver operating characteristic(ROC)curve was plotted to obtain cutoff values for each risk factor and evaluate their predictive value for osteochondral injury.Results:Among 155 affected joints,there were a total of 108 joints with osteochondral injury and 47 joints without osteochondral injury.The synovial thickness measured by conventional ultrasound was significantly positively correlated with cartilage and bone scores(r=0.66,0.69);the SMI parameter synovial vascular index(VI)was significantly positively correlated with cartilage and bone scores(r=0.61,0.67).Multivariate Logistic regression analysis showed that patient age,synovial thickness,and synovial VI were independent risk factors for osteochondral injury.The ROC curve showed that the area under the curve for predicting osteochondral injury was 0.74,0.90,and 0.91,respectively.Based on the cutoff values of age≥19 years,joint synovial thickness≥3.95 mm,and synovial VI≥2.35%,osteochondral injury was indicated,with sensitivities of 85.0%,85.8%and 76.7%,and specificities of 60.0%,85.7%and 97.1%,respectively.Conclusion:The assessment of hemophilic synovitis using conventional ultrasound combined with SMI can effectively predict the risk of osteochondral injury.This has significant value for early monitoring and intervention of synovitis and the prevention of osteochondral injury.关键词
滑膜炎/骨折,软骨/超声检查Key words
Synovitis/Fractures,Cartilage/Ultrasonography分类
医药卫生引用本文复制引用
赵宇心,周鸿,周洋,叶鸣,刘莹,曾欣..常规超声联合超微血流成像评估血友病性滑膜炎在骨软骨损伤风险预测中的应用价值[J].中国临床医学影像杂志,2025,36(3):213-217,5.基金项目
四川省医学科研课题(课题号:S18068). （课题号:S18068）
