摘要
Abstract
Objective To explore the aesthetic effects of yeast recombinant collagen liquid dressing combined with salicylic acid peeling in the treatment of facial acne.Methods A total of 160 patients with facial acne were enrolled between March 2022 and August 2023.Patients were randomly assigned to an observation group and a control group,with 80 patients in each group.The control group received yeast recombinant collagen liquid dressing,while the observation group was additionally treated with salicylic acid peeling.Clinical efficacy,skin barrier function indices[stratum corneum water content(SCWC),epidermal sebum content(ESC),transepidermal water loss(TEWL),pH],symptom improvement(duration of wound pain,crusting time,and desquamation time),aesthetic effects[Vancouver scar scale(VSS)],and skin microbiota diversity[species abundance indices:Chao1 index,Pielou's evenness index,Simpson index,Shannon index]were compared between the two groups..Results The total response rate in the observation group(90.00%)was significantly higher than that in the control group(77.50%)(P＜0.05).After treatment,the observation group showed higher SCWC and ESC,and lower TEWL and pH compared to the control group(P＜0.05).The duration of wound pain,crusting time,and desquamation time in the observation group were significantly shorter than those in the control group(P＜0.05).Additionally,the VSS scores in all dimensions were significantly lower in the observation group compared to the control group(P＜0.05).Post-treatment,the Pielou E,Simpson,and Shannon indices in the observation group were significantly lower than in the control group(P＜0.05),while there was no significant difference in the Chao1 index between the two groups(P＞0.05).Conclusion The aesthetic effect of yeast recombinant collagen liquid dressing combined with salicylic acid peeling is significant in the treatment of facial acne,which can effectively improve skin barrier function,accelerate remission of clinical symptoms,improve aesthetic effect and the stability of skin microflora.关键词
面部痤疮/水杨酸/酵母重组胶原蛋白液体敷料/美学效果Key words
facial acne/salicylic acid/yeast recombinant collagen liquid dressing/aesthetic effect分类
医药卫生
