中国美容医学2025，Vol.34Issue(3)：98-102,5.
点阵铒激光联合艾拉-光动力疗法治疗面部痤疮的美学效果观察
Aesthetic Effect of Er∶YAG Fractional Laser Combined with Aminolevulinic Acid-photodynamic Therapy in Treating Facial Acne
马建颖 1杨春香 1胡新红 1蔺建苹 1王娜 1赵华 1赵静1
作者信息
- 1. 空军军医大学第二附属医院皮肤科 陕西 西安 710038
- 折叠
摘要
Abstract
Objective To observe the aesthetic effect of erbium-doped yttrium aluminum garnet(Er∶YAG)fractional laser combined with aminolevulinic acid-photodynamic therapy(ALA-PDT)in the treatment of facial acne,compared with ALA-PDT.Methods 102 patients with facial acne in the author's hospital were selected from January 2020 to January 2023,and were randomly divided into control group(n=51)and observation group(n=51).The control group was treated with ALA-PDT,while the observation group was given Er∶YAG fractional laser on the basis of the control group.The clinical efficacy,facial acne status[Global Ache Grading System(GAGS)score],facial scar status[Vancouver Scar Scale(VSS)score],inflammatory factors[interleukin(IL)-17,IL-18,interferon-γ(IFN-γ)]and adverse reactions were observed in the two groups after treatment.Results The total effective rate of clinical efficacy in observation group after treatment was significantly higher than that in control group(P＜0.05).After treatment,the GAGS score,VSS score and levels of IL-17 and IL-18 in both groups were significantly declined compared with those before treatment(P＜0.05),and the above scores and levels were significantly lower in observation group than those in control group(P＜0.05).The INF-level in the two groups after treatment was significantly risen than that before treatment(P＜0.05),and the observation group had significantly higher IFN-γ level(P＜0.05).There was no significant difference in the total incidence rate of adverse reactions between groups during treatment(P＞0.05).Conclusion Er∶YAG fractional laser combined with ALA-PDT has a significant effect in the treatment of facial acne.It can effectively relieve the facial acne and scar severity,inhibit the inflammatory response and has good safety..关键词
点阵铒激光/艾拉-光动力疗法/面部痤疮/美学效果Key words
Er∶YAG/Aminolevulinic acid-photodynamic therapy/Facial acne/Aesthetic effect分类
医药卫生引用本文复制引用
马建颖,杨春香,胡新红,蔺建苹,王娜,赵华,赵静..点阵铒激光联合艾拉-光动力疗法治疗面部痤疮的美学效果观察[J].中国美容医学,2025,34(3):98-102,5.
