中国美容医学2025，Vol.34Issue(3)：112-115,4.
超脉冲点阵CO2激光序贯黄金微针射频联合rb-bFGF凝胶治疗面部凹陷性痤疮瘢痕临床分析
Clinical Analysis of Ultra-pulse Fractional CO2 Laser Combined with Gold Microneedle Radiofrequency and rb-bFGF Gel in Atrophic Acne Scars
摘要
Abstract
Objective To evaluate the clinical efficacy of ultra-pulse fractional CO2 laser combined with gold microneedle radiofrequency and recombinant bovine basic fibroblast growth factor(rb-bFGF)gel in the treatment of facialatrophic acne scars.Methods A total of 150 patients with atrophic acne scars were recruited from the Medical Aesthetics Department of Chengde Maternal and Child Health Hospital.between June 2022 and October 2023.Using a random number table,the patients were divided into three groups:control group 1(50 cases,treated with ultra-pulse fractional CO2 laser),control group 2(50 cases,treated with ultra-pulse fractional CO2 laser and rb-bFGF gel),and observation group(50 cases,treated with ultra-pulse fractional CO2 laser,rb-bFGF gel,and gold microneedle radiofrequency).The efficacy,severity of acne scars,facial aesthetic improvement,and adverse reactions were compared among the three groups.Results After treatment,the total effective rate of observation group(94.00%)was significantly higher than that of control group 1(76.00%)and control group 2(80.00%)(P＜0.05).The acne scar score of the three groups after treatment was lower than that before treatment,and the observation group was lower than control group 1 and control group 2(P＜0.05).After treatment,the melanin index and heme index of the three groups were lower than before treatment,and the water content of the skin stratum corneum was higher than before treatment,and the melanin index and heme index of the observation group were more significantly reduced,and the water content of the skin stratum corneum was more significantly increased(P＜0.05).During treatment,there was no significant difference in adverse reactions among the three groups(P＞0.05).Conclusion The combination of ultra-pulse fractional CO2 laser,gold microneedle radiofrequency,and rb-bFGF gel is an effective and safe treatment for moderate to severeatrophic acne scars,offering significant improvement in facial aesthetics and acne scar severity with minimal adverse reactions.关键词
凹陷性痤疮瘢痕/重组牛碱性成纤维细胞生长因子/超脉冲点阵二氧化碳激光/黄金微针射频/美观度Key words
atrophic acne scars/recombinant bovine basic fibroblast growth factor/ultra-pulse fractional CO2 laser/gold microneedle radiofrequency/aesthetics分类
医药卫生引用本文复制引用
祁莹莹,李超,王红..超脉冲点阵CO2激光序贯黄金微针射频联合rb-bFGF凝胶治疗面部凹陷性痤疮瘢痕临床分析[J].中国美容医学,2025,34(3):112-115,4.基金项目
承德市科技计划项目(编号:202301A002) （编号:202301A002）
