摘要
Abstract
Objective To explore the effect of intense pulse light combined with Q-switched laser on skin physiological parameters and cosmetic effects in patients with post-acne hyperpigmentation.Methods Ninety-three patients with post-acne hyperpigmentation attending the author's hospital from January 2021 to December 2022 were enrolled,and assigned to either intense pulse light(IPL group),Q-switched laser(laser group)or intense pulse light combined with Q-switched laser(joint group)using the lottery method,each with 31 cases.Then the scores of pigmentation degree,skin physiological parameters,cosmetic effects,and quality of life were compared among the three groups after treatment.Results The effective rate of cosmetic effect of patients in the intense pulsed light group was 74.19%,the effective rate of the Q-switched laser group was 77.42%,and the effective rate of the combined treatment group was 93.55%.The effective rate of the combined treatment group was higher than that of the intense pulsed light group(χ2=4.292,P<0.05),there was no significant difference between other groups(P>0.05).After treatment,a reduction in pigmentation degree,transepidermal water loss rate(TEWL),sebum excretion and Dermatology Life Quality Index(DLQI),as well as an increase in hydration of stratum corneum and skin surface pH were observed in all three groups(P<0.05),and above improvements were all more notable in joint group compared to IPL group and laser group(P<0.05).Conclusion Application of intense pulse light combined with Q-switched laser in patients with post-acne hyperpigmentation has good cosmetic effect,which can effectively alleviate the degree of pigmentation,ameliorate the skin physiological parameters and improve the quality life.关键词
强脉冲光/色素沉着/痤疮/美学效果/调Q激光Key words
intense pulse light/hyperpigmentation/acne/aesthetic effect/Q-switched laser分类
医药卫生