中国现代医学杂志2025，Vol.35Issue(5)：53-59,7.DOI:10.3969/j.issn.1005-8982.2025.05.009
重度哮喘的生物标志物研究进展
Advances in biomarker research for severe asthma
摘要
Abstract
Severe asthma,characterized as a complex and heterogeneous chronic inflammatory disease,has witnessed significant advancements in biomarker research alongside a deepening understanding of its pathogenesis in recent years.These advancements have markedly improved diagnostic and therapeutic strategies for this condition.Each biomarker contributes uniquely to precision medicine in severe asthma by providing critical insights into its molecular underpinnings.This review synthesizes the latest global research progress on existing and emerging omics-based biomarkers that hold promise for refining the management of severe asthma.These biomarkers rapidly elucidate disease-specific pathophysiological pathways,thereby offering robust evidence to guide precision diagnosis and tailored therapeutic approaches.Furthermore,we highlight future directions in biomarker discovery,emphasizing their potential to overcome current limitations in phenotyping and therapeutic resistance.关键词
重度哮喘/生物标志物/未来方向Key words
severe asthma/biomarkers/future directions分类
临床医学引用本文复制引用
刘辉,孔晓梅..重度哮喘的生物标志物研究进展[J].中国现代医学杂志,2025,35(5):53-59,7.基金项目
国家自然科学基金(No:82370024) （No:82370024）
