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代谢相关脂肪性肝病与慢性肾脏病的研究进展

于明睿 刘向春 肖娟 柳刚

中国现代医学杂志2025,Vol.35Issue(6):39-44,6.
中国现代医学杂志2025,Vol.35Issue(6):39-44,6.DOI:10.3969/j.issn.1005-8982.2025.06.007

代谢相关脂肪性肝病与慢性肾脏病的研究进展

Research advances in the relationship between metabolic dysfunction-associated fatty liver disease and chronic kidney disease

于明睿 1刘向春 1肖娟 2柳刚3

作者信息

  • 1. 山东大学第二医院 肾脏多学科创新医学中心,山东济南 250033
  • 2. 山东大学第二医院,山东济南 250033
  • 3. 山东大学生殖内分泌教育部重点实验室,山东济南 250012
  • 折叠

摘要

Abstract

Metabolic dysfunction-associated fatty liver disease(MAFLD)is a chronic metabolic dysfunction-related liver injury characterized by excessive fat accumulation in the liver,and its global prevalence is increasing year by year.There is growing evidence of a strong association between MAFLD and chronic kidney disease(CKD).Although the mechanism between the two has not been fully elucidated,many studies indicate that metabolic dysfunction,gut microbiota imbalance,and genetic factors may play an important role.This review summarizes the clinical evidence of the association between MAFLD and CKD,and the possible mechanisms by which MAFLD increases the risk of CKD.

关键词

慢性肾脏病/代谢相关脂肪性肝病/研究进展

Key words

chronic kidney disease/metabolic dysfunction-associated fatty liver disease/research advances

分类

临床医学

引用本文复制引用

于明睿,刘向春,肖娟,柳刚..代谢相关脂肪性肝病与慢性肾脏病的研究进展[J].中国现代医学杂志,2025,35(6):39-44,6.

基金项目

国家自然科学基金(No:82370720) (No:82370720)

中国现代医学杂志

1005-8982

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