摘要
Abstract
Objective To investigate the effect of triamcinolone and botox type A on the treatment of hypertrophic scar(HS).Methods A total of 84 patients with HS admitted to Xinxiang Central Hospital from June 2021 to June 2024 were selected and divided into 2 groups with 42 cases in each group according to the treatment method is different.The control group was treated with triamcinolone injection,and the observation group was treated with triamcinolone injection combined with botox type A.The clinical efficacy,serum cytokine level,scar index,pain degree and adverse reactions were compared between the two groups.Results After treatment,the total effective rate 95.24%and bone morphogenetic protein 7(335.94±20.39)ng/L in the observation group were higher than those in the control group 80.95%and(304.59±18.86)ng/L.Serum transforming growth factor(189.62±12.74)ng/L,Vancouver Scar Scale color(0.86±0.20),(1.42±0.36),(0.92±0.24),(1.74±0.36),visual analogue scale(3.62±0.37)score was lower than that of control group(237.54±16.85)ng/L,(1.62±0.39),(2.05±0.48),(1.58±0.37),(2.69±0.50),(4.94±0.59),and there was statistical significance(P<0.05).There was no statistical significance in adverse reactions between the two groups(P>0.05).Conclusions Triamcinolone and botox A are effective in the treatment of HS patients,which can improve the level of serum cytokines and scar,reduce the degree of pain,and have few adverse reactions.关键词
增生性瘢痕/曲安奈德/A型肉毒毒素/血清细胞因子水平/瘢痕Key words
hypertrophic scar/triamcinolone/botulinum toxin type A/serum cytokine levels/cicatrix
