中国医学科学院学报2025，Vol.47Issue(1)：16-22,7.DOI:10.3881/j.issn.1000-503X.16120
淋巴管超声造影与静脉超声造影在鉴别诊断甲状腺癌颈部转移淋巴结中的应用
Lymphatic and Venous Contrast-Enhanced Ultrasound Imaging for Differential Diagnosis of Cervical Lymph Node Metastasis in Thyroid Cancer
摘要
Abstract
Objective To investigate the value of the novel lymphatic contrast-enhanced ultrasound(LCEUS)and conventional venous contrast-enhanced ultrasound(VCEUS)in the differential diagnosis of benign and malignant cervical lymph nodes in patients with thyroid cancer.Methods Patients with suspected thyroid cancer underwent conventional ultrasound,VCEUS,and LCEUS examinations of cervical lymph nodes before biopsy.The diagnostic abilities of conventional ultrasound,VCEUS,and LCEUS were compared with pathological results as the golden standard.Results Forty-four patients with 52 lymph nodes were included in the final data.Thirty-eight metastatic lymph nodes were confirmed by pathological results,and 14 were benign.The diagnostic sensitivity,specificity,and accuracy were 97.37%,71.43%,and 90.38%for LCEUS,92.11%,35.71%,and 76.92%for VCEUS,and 94.74%,21.43%,and 75.00%for conventional ultrasound,respectively.The area under the curve of LCEUS analyzed by the receiver operating characteristic curve was grea-ter than that of VCEUS(P=0.020)and conventional ultrasound(P<0.001).Conclusion LCEUS could significantly improve the differential diagnosis of cervical lymph node metastasis in the patients with thyroid canc-er,providing a basis for precise clinical treatment.关键词
甲状腺/超声/超声造影/淋巴结Key words
thyroid/ultrasound/contrast-enhanced ultrasound imaging/lymph node分类
临床医学引用本文复制引用
李旭,万文博,高天,苟涛华,张艳..淋巴管超声造影与静脉超声造影在鉴别诊断甲状腺癌颈部转移淋巴结中的应用[J].中国医学科学院学报,2025,47(1):16-22,7.基金项目
国家自然科学基金(81901746) （81901746）
