中国医学科学院学报2025，Vol.47Issue(1)：48-54,7.DOI:10.3881/j.issn.1000-503X.16050
腹部CT联合血清学指标对特发性腹膜后纤维化输尿管受累的预测价值
Predictive Value of Abdominal CT Images Combined With Serological Indicators for Ureteral Involvement in Idiopathic Retroperitoneal Fibrosis
王婷婷 1姜超 2李宁 2孙露露 2田卢峰 2吴哲2
作者信息
- 1. 锦州医科大学抚顺市中心医院研究生培养基地,辽宁抚顺 113006
- 2. 抚顺市中心医院放射科,辽宁抚顺 113006
- 折叠
摘要
Abstract
Objective To analyze the value of abdominal CT images combined with serological indica-tors in predicting the ureteral involvement in idiopathic retroperitoneal fibrosis(IRF).Methods The CT ima-ges of 79 IRF patients were analyzed retrospectively,including the involved sites and enhancement characteristics of the lesions.According to the inclusion and exclusion criteria,43 patients with complete serological data were selected and assigned into a ureteral involvement group(n=29)and a non-ureteral involvement group(n=14)according to whether ureters were involved in IRF.Logistic regression analysis was performed to select independent risk factors for ureteral involvement in IRF.The receiver operating characteristic(ROC)curve was plotted to eval-uate the predictive value of the CT arterial phase enhancement magnitude and serum cystatin C(CysC)for ureteral involvement in IRF.Results The CT images of IRF usually showed a soft tissue density lesion encompassing the abdominal aorta,iliac arteries,ureters,and retroperitoneal tissue,with a wide range of distribution.The ureteral involvement group and the non-ureteral involvement group showed differences in gender(P=0.031),CT arterial phase enhancement amplitude(P=0.014),CT venous phase enhancement amplitude(P=0.032),and serum CysC(P=0.036).Logistic regression analysis showed that gender(P=0.034),CT arterial phase enhancement amplitude(P=0.046),and serum CysC(P=0.041)were independent risk factors for ureteral involvement in IRF.The area under the curve for CT arterial phase enhancement combined with serum CysC to predict ureteral involvement in IRF was 0.776.Ten patients had lower levels of erythrocyte sedimentation rate(P<0.001),C-reactive protein(P=0.021),and IgG4(P<0.001)in the follow-up period than before treatment.Conclusion The combination of abdominal CT images with serological indicators demonstrates high accuracy in predicting the ureteral involvement in IRF,providing reference for early clinical diagnosis.关键词
特发性腹膜后纤维化/IgG4相关性疾病/CT/影像诊断/血清学Key words
idiopathic retroperitoneal fibrosis/IgG4-related disease/CT/diagnostic imaging/serology分类
临床医学引用本文复制引用
王婷婷,姜超,李宁,孙露露,田卢峰,吴哲..腹部CT联合血清学指标对特发性腹膜后纤维化输尿管受累的预测价值[J].中国医学科学院学报,2025,47(1):48-54,7.
