中国医学科学院学报2025,Vol.47Issue(1):146-149,4.DOI:10.3881/j.issn.1000-503X.15997
宏基因组高通量测序辅助诊断日本斑点热一例
Metagenomic Next-Generation Sequencing-Assisted Diagnosis of Japanese Spotted Fever:Report of One Case
阮永春 1周宜庆 1张海旺 1周洁 1段金楠 1张晓静 2李明晖1
作者信息
- 1. 绍兴市人民医院感染性疾病科,浙江 绍兴 312000
- 2. 微岩医学科技(北京)有限公司,北京 100023
- 折叠
摘要
Abstract
Japanese spotted fever(JSF)is an infectious disease caused by Rickettsia japonica,with nonspecific clinical symptoms and a high risk of misdiagnosis.We reported a case of JSF,in which Rickettsia ja-ponica was detected in blood cells by metagenomic next-generation sequencing.The patient recovered after treat-ment with doxycycline.This report provides a reference for the clinical diagnosis and treatment of JSF.关键词
日本立克次体/日本斑点热/诊断/宏基因组高通量测序Key words
Rickettsia japonica/Japanese spotted fever/diagnosis/metagenomic next-generation sequencing分类
医药卫生引用本文复制引用
阮永春,周宜庆,张海旺,周洁,段金楠,张晓静,李明晖..宏基因组高通量测序辅助诊断日本斑点热一例[J].中国医学科学院学报,2025,47(1):146-149,4.