中国医院用药评价与分析2025,Vol.25Issue(2):137-142,6.DOI:10.14009/j.issn.1672-2124.2025.02.003
基于数据挖掘探讨明清新安医家治疗噎膈的用药规律及学术思想
Medication Rules and Academic Thoughts of Xin'an Doctors in the Treatment of Choking and Diaphragm in the Ming and Qing Dynasties Based on Data Mining
摘要
Abstract
OBJECTIVE:To explore the medicine rules and academic thoughts of Xin'an doctors in the treatment of choking and diaphragm in the Ming and Qing dynasties,so as to provide reference for modern clinical practice.METHODS:The prescriptions for the treatment of choking and diaphragm in Shishan Medical Records,Medical Reading,Famous Medical Cases,and the Complete Collection of Ancient and Modern Medical Systems written by Xin'an doctors in the Ming and Qing dynasties were selected,and the database was established with the help of Microsoft Excel 2021.SPSS Statistics 26.0 software and R software(4.3.3 version)were used for data analysis.RESULTS:A total of 153 prescriptions and 195 flavors of traditional Chinese medicine were included,with a total frequency of 1 165,and 20 flavors of high-frequency drugs(frequency>10%).The main categories of drugs were deficiency tonifying drugs,Qi regulating drugs and dampness-clearing drugs.The drug properties were mainly warm.The taste of medicine was mainly sweet,spicy and bitter.The main channels were stomach,spleen and liver.Among the association rules,the two,three and four association rules with the highest degree of support were"Poria cocos-Atractylodes macrocephala koidz""Citrus reticulata-Arum ternatum thunb-Poria cocos"and"Panax Ginseng-Atractylodes macrocephala koidz-Poria cocos-Citrus reticulata".The cluster analysis showed that there were two kinds of decoction,namely Erchen decoction and Xiaobanxia decoction.Factor analysis obtained 6 common factors,3 new prescriptions,namely Sijunzi decoction,Renshen Lige pills,and Xiangsha Kuanzhong pills.CONCLUSIONS:Choking and diaphragm are more of the deficiency standard,with Qi stagnation and phlegm turbidity.Xinan doctors put"Zaoshi Huatan""Xingqi Kaiyu""Yiqi Jianpi"and"Wenzhong Zhitong"principles throughout the treatment,reflecting the academic thoughts of treating both symptoms and root causes.关键词
噎膈/明清新安医家/数据挖掘/用药规律/学术思想Key words
Choking and diaphragm/Xin'an doctors in Ming and Qing dynasties/Data mining/Medication rules/Academic thoughts分类
医药卫生引用本文复制引用
赵婉竹,任涵,魏科东,吴婉婉,徐少华,黄金玲..基于数据挖掘探讨明清新安医家治疗噎膈的用药规律及学术思想[J].中国医院用药评价与分析,2025,25(2):137-142,6.基金项目
国家自然科学基金面上项目(No.81573864) (No.81573864)