中国资源综合利用2025，Vol.43Issue(2)：16-23,8.DOI:10.3969/j.issn.1008-9500.2025.02.006
固相萃取液相色谱-三重四极杆质谱仪测定水中7种烷基酚类和双酚类化合物
Determination of Seven Alkylphenols and Bisphenol Compounds in Water by Solid Phase Extraction Liquid Chromatography-Triple Quadrupole Mass Spectrometry
摘要
Abstract
In this experiment,a method for analyzing seven alkylphenols(octylphenol,4-octylphenol,nonylphenol,4-nonylphenol)and bisphenol compounds(bisphenol A,bisphenol B,bisphenol F)in water using high-performance liquid chromatography is proposed by optimizing the pretreatment process and mass spectrometry conditions.The sample is filtered using a quartz filter membrane with a pore size of 0.45 μm,and the sample is pretreated using a styrene/divinylbenzene copolymer chromatography column solid-phase extraction column.The column temperature is set to 40℃,the flow rate is set to 0.3 mL/min,methanol and ammonia water are used as mobile phases,and gradient elution is used for separation,and liquid chromatography tandem mass spectrometry Multiple Reaction Monitoring(MRM)negative ion mode is used for determination,and internal standard method is used for quantification.The results show that within the concentration detection range of 0.1～50.0 μg/L,the standard curves of 7 alkylphenols and bisphenol compounds show good linearity(correlation coefficient r＞0.999).The relative standard deviation of the spiked samples with low,medium,and high concentrations remained between 2.6%and 17.2%,the recovery rate ranged from 75%to 102%,and the method detection limit was 0.000 06～0.000 10 μg/L.The test results indicate that this method is suitable for practical detection of surface water,groundwater,and drinking water.关键词
固相萃取/高效液相色谱/三重四极杆质谱仪/烷基酚/双酚Key words
solid phase extraction/high performance liquid chromatography/triple quadrupole mass spectrometer/alkylphenol/bisphenol分类
资源环境引用本文复制引用
甘杰,丰小阳,王国庆,蒋开年,熊芬,魏凤..固相萃取液相色谱-三重四极杆质谱仪测定水中7种烷基酚类和双酚类化合物[J].中国资源综合利用,2025,43(2):16-23,8.基金项目
湖南省环保科研课题(HBKT-2002006) （HBKT-2002006）
国家可持续发展议程创新示范区建设省级专项(2021sfq26). （2021sfq26）
