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黄蜀葵花化学成分、药理活性研究进展及质量标志物的预测分析

关诗涵 王喜军 刘畅 颜晓桐 韩金伟 尹凤婷 孙晖 闫广利 孔玲 韩莹

中国中药杂志2025,Vol.50Issue(4):908-921,14.
中国中药杂志2025,Vol.50Issue(4):908-921,14.DOI:10.19540/j.cnki.cjcmm.20241126.201

黄蜀葵花化学成分、药理活性研究进展及质量标志物的预测分析

Research progress in chemical constituents and pharmacological activities of Abelmoschi Corolla and prediction of its quality markers

关诗涵 1王喜军 1刘畅 1颜晓桐 1韩金伟 1尹凤婷 1孙晖 1闫广利 1孔玲 1韩莹1

作者信息

  • 1. 黑龙江中医药大学 经方与现代中药融合创新全国重点实验室 国家中医药管理局中医方证代谢组学研究中心,黑龙江 哈尔滨 150040
  • 折叠

摘要

Abstract

Abelmoschi Corolla,the dried corolla of Abelmoschus manihot,has anti-inflammatory,antioxidant,and anti-fibrosis activities.Its chemical constituents mainly include flavonoids,organic acids,steroids,and polysaccharides.This study reviewed the research progress in the chemical constituents and pharmacological activities of Abelmoschi Corolla in recent 20 years.According to the concept of quality marker(Q-marker),the Q-markers of Abelmoschi Corolla were predicted from plant phylogeny,chemical constituent specificity,traditional efficacy,chemical constituent measurability,and absorbed constituents.The primary Q-markers for Abelmoschi Corolla were anticipated to include quercetin-3′-O-β-D-glucopyranoside,gossypetin-8-O-β-D-glucuronide,isoquercetin,myricetin,quercetin,and hyperoside,with the aim of providing reference data for improving the quality evaluation system of Abelmoschi Corolla.

关键词

黄蜀葵花/化学成分/药理活性/作用机制/质量标志物

Key words

Abelmoschi Corolla/chemical constituent/pharmacological activity/mechanism of action/quality marker

引用本文复制引用

关诗涵,王喜军,刘畅,颜晓桐,韩金伟,尹凤婷,孙晖,闫广利,孔玲,韩莹..黄蜀葵花化学成分、药理活性研究进展及质量标志物的预测分析[J].中国中药杂志,2025,50(4):908-921,14.

基金项目

国家自然科学基金项目(32141005) (32141005)

中国中药杂志

OA北大核心

1001-5302

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